105337-38-0

Upstream product

• 503-74-2 3-methylbutyric acid 
• 108-39-4 3-methyl-phenol 
• 105401-73-8 3-methylphenyl 3-methylbutyrate 
• 110411-30-8 2,2,7-trimethylchroman-4-one 
• 78-77-3 Isobutyl bromide 
• 18495-14-2 2-hydroxy-4-methylbenzonitrile 
• 108-12-3 isopentanoyl chloride 

Downstream Products

• 107057-45-4 2-Isopentyl-5-methyl-phenol 
• 71898-88-9 2-methoxy-4-methylisovalerophenone 
• 125042-01-5 2-bromo-3-methyl-1-(2-methoxy-4-methylphenyl)-1-butanone 
• 125041-98-7 4-methyl-3-(2-methoxy-4-methylbenzyl)-pentanoic acid 
• 125041-97-6 4-methyl-3-(2-methoxy-4-methylbenzoyl)-pentanoic acid 

Relevant academic research and scientific papers

Relay Catalysis by Achiral Borane and Chiral Phosphoric Acid in the Metal-Free Asymmetric Hydrogenation of Chromones

A strategy of relay catalysis by achiral borane and chiral phosphoric acid was successfully developed for the asymmetric hydrogenation of chromones, giving the desired products in high yields with up to 95% ee. Achiral borane and chiral phosphoric acid are highly compatible in this reaction. The achiral borane acts as a Lewis acid for the first-step hydrogenation, and the chiral phosphoric acid acts as an effective chiral proton shuttle to control the enantioselectivity.

Chromenes and chromanones. Part IV.1 The Birch reduction of 2,2-dimethyl-4-chromanone and its 7-substituted analogues

2,2-Dimethyl-4-chromanone (1a), 2,2,7-trimethyl-4-chromanone (1b) and 7-methoxy-2,2-dimethyl-4-chromanone (1c) have been reduced by sodium or lithium in liquid ammonia with the presence or without of proton donor. The bicyclic or phenolic products were obtained. Products with reduced benzene ring only were also observed. The possible mechanisms of reductions are considered.

Studies on Aromatic Sesquiterpenes. XI. Synthesis of 7-Isopropyl-3,5-dimethyl-1-naphthol

Starting from m-cresol, the title new naphthol was synthesized through 4-methyl-3-(2-methoxy-4-methylbenzoyl)pentanoic acid as a key intermediate.