10541-33-0

Basic information

• Product Name: N-Methyl-p-anisidine hydrochloride ,98%
• Synonyms: N-Methyl-p-anisidine hydrochloride ,98%;4-Methoxy-N-methylaniline HCl;BenzenaMine, 4-Methoxy-N-Methyl-, hydrochloride;4-Methoxy-N-Methylaniline hydrochloride;N-Methyl-p-anisidine hydrochloride;4-Methoxy-N-methylbenzenamine hydrochloride
• CAS NO: 10541-33-0
• Molecular Formula: C₈H₁₁NO*ClH
• Molecular Weight: 173.63998
• Mol File: 10541-33-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 119-120 °C
• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: N-Methyl-p-anisidine hydrochloride ,98%(CAS DataBase Reference)
• NIST Chemistry Reference: N-Methyl-p-anisidine hydrochloride ,98%(10541-33-0)
• EPA Substance Registry System: N-Methyl-p-anisidine hydrochloride ,98%(10541-33-0)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 10541-33-0(Hazardous Substances Data)

Usage

Chemical Properties

Light purple powder

Upstream product

• 64317-34-6 N-(pentafluorophenyl)carbonimidoyl dichloride 
• 5961-59-1 N-methyl-N-(4-methoxyphenyl)amine 
• 3424-93-9 4-methoxyphenylacetamide 
• 14803-72-6 methyl N-(4-methoxyphenyl)carbamate 

Downstream Products

• 150784-52-4 N-(4-methoxy-phenyl)-N-methyl-guanidine 
• 299915-71-2 2-chloro-4-methoxy-N-methylaniline 
• 42040-25-5 6-methoxy-3-methyl-2-iminobenzothiazoline 
• 32417-67-7 N-(4-methoxy-phenyl)-N-methyl-thiourea 

Relevant articles and documents

Method for preparing amine compound by reducing amide compound

The invention relates to a method for preparing an amine compound by reducing an amide compound, which comprises the following steps: in a protective atmosphere, mixing the amide compound or cyclic amide, a zirconium metal catalyst and pinacol borane, carrying out amide reduction reaction at room temperature, and carrying out aftertreatment by using an ether solution of hydrogen chloride after 12-48 hours to obtain an amine hydrochloride compound. The method is simple to operate, low in cost, good in functional group tolerance and wide in substrate range.

REACTIONS OF N-POLYFLUOROPHENYLCARBONIMIDOYL DICHLORIDES WITH PRIMARY AND SECONDARY AMINES. KINETICS AND MECHANISM. SYNTHESIS OF POLYFLUORINATED CABODIIMIDES, CHLOROFORMAMIDINES, GUANIDINES AND BENZIMIDAZOLES

The reactions of N-polyfluorophenylcarbonimidoyl dichlorides with primary and secondary aliphatic and aromatic amines have been studied.With primary aliphatic amines, the reactions led to carbodiimides or guanidines, depending on the amount of amine.The carbodiimides obtained reacted with amines to form guanidines.The reactions with primary aromatic amines produced only triarylguanidines.N-Pentafluorophenylcarbonimidoyl dichloride (I) reacted with tetrafluoro-o-phenylene diamine to give 2-pentafluoroanilino-4,5,6,7-tetrafluorobenzimidazole.Polyfluorinated benzimidazole derivatives were also produced by the thermolysis of polyfluorinated triarylguanidines.Heating of N1,N2,N3-tris(pentafluorophenyl)guanidine with K2CO3 in dimethylformamide led to 1,2,3,4,7,8,9,10-octafluoro-5-pentafluorophenyl-5H-benzimidazobenzimidazole.N-Polyfluorophenylcarbonimidoyl dichlorides reacted with various secondary amines alredy at room temperature giving N-polyfluorophenylchloroformamidines in high yields.Elevated temperature and prolonged reaction time led to formation of N-polyfluorophenylguanidines.Kinetics and mechanism of the reactions of N-polyfluorophenylcarbonimidoyl dichlorides with primary and secondary amines in acetonitrile at 25 deg C have been studied.The reactions have been found to proceed by a bimolecular nucleophilic addition-elimination mechanism via a tetrahedral intermediate.Possible reasons of formation of different products in the above transformations are discussed in terms of this mechanism.