105436-18-8Relevant articles and documents
Pd-catalyzed arylation of chlorotrifluoroethylene using arylboronic acids
Yamamoto, Tetsuya,Yamakawa, Tetsu
supporting information; experimental part, p. 3454 - 3457 (2012/08/29)
The palladium-catalyzed cross-coupling of chlorotrifluoroethylene and arylboronic acids proceeds in the presence of a base and H2O to provide α,β,β-trifluorostyrene derivatives in satisfactory yields.
A remarkable room temperature preparation of the trifluorovinylzinc reagent from HFC-134a. A cost-effective, high yield synthesis of α,β,β-trifluorostyrenes
Anilkumar,Burton, Donald J
, p. 2731 - 2733 (2007/10/03)
The reaction of LDA (2.0 equiv.) with a THF solution of ZnCl2 (1.0 equiv.) and CF3CFH2 (HFC-134a) (1.2 equiv.) at 15-20°C gives a 73% yield of [F2C=CFZnCl]. Addition of R-C6H4I and Pd(PPhs
PALLADIUM CATALYZED COUPLING OF F-VINYL ZINC REAGENTS WITH ARYL IODIDES. AN IMPROVED SYNTHESIS OF α,β,β-TRIFLUOROSTYRENES AND THE STEREOSPECIFIC PREPARATION OF 1-PHENYL-F-PROPENES
Heinze, Pamela L.,Burton, Donald J.
, p. 115 - 120 (2007/10/02)
Palladium catalyzed coupling of trifluorovinyl zinc reagents with substituted aryl iodides provides a practical high yield route to α,β,β-trifluororstyrenes.Ortho, meta, and para substituted aryl iodides all work equally well.Similar coupling with E- and Z-1-iodo-F-propenes outlines the first stereospecific preparative route to 1-aryl-F-olefins.This approach provides a rapid, easily scaled-up synthesis via a one pot procedure to these valuable styrenes from commercially available precursors without recourse to low temperature processes or the use of unstable reaction intermediates.
