1054617-67-2

Basic information

• Product Name: (R)-4-Benzyl-3-{(E)-(S)-2-[(1S,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-4-phenylselanyl-butyl]-3,7-dimethyl-octa-3,6-dienoyl}-oxazolidin-2-one
• Synonyms: (R)-4-Benzyl-3-{(E)-(S)-2-[(1S,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-4-phenylselanyl-butyl]-3,7-dimethyl-octa-3,6-dienoyl}-oxazolidin-2-one
• CAS NO: 1054617-67-2
• Molecular Weight: 690.738
• Mol File: 1054617-67-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-Benzyl-3-{(E)-(S)-2-[(1S,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-4-phenylselanyl-butyl]-3,7-dimethyl-octa-3,6-dienoyl}-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-Benzyl-3-{(E)-(S)-2-[(1S,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-4-phenylselanyl-butyl]-3,7-dimethyl-octa-3,6-dienoyl}-oxazolidin-2-one(1054617-67-2)
• EPA Substance Registry System: (R)-4-Benzyl-3-{(E)-(S)-2-[(1S,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-4-phenylselanyl-butyl]-3,7-dimethyl-octa-3,6-dienoyl}-oxazolidin-2-one(1054617-67-2)

Safety Data

• Hazardous Substances Data: 1054617-67-2(Hazardous Substances Data)

Upstream product

• 364337-18-8 methyl (2R)-2-p-methoxybenzyloxy-4-phenylselanylbutanoate 
• 16750-94-0 2,6-dimethyl-2,5-octadien-8-ol 
• 364337-19-9 (2R)-2-p-methoxybenzyloxy-4-phenylselanylbutanal 
• 364337-20-2 (4R)-4-benzyl-3-[(3E)-(3,7-dimethylocta-3,6-dienoyl)]-oxazolidin-2-one 
• 364337-17-7 methyl (2R)-2-hydroxy-4-phenylselanylbutanoate 
• 364337-16-6 (3E)-3,7-dimethyl-octa-3,6-dienoic acid 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 372504-89-7 (R)-4-benzyl-2-oxazolidinone lithium salt 
• 1666-13-3 diphenyl diselenide 

Downstream Products

• 364337-23-5 (2S)-2-[(1S,2R)-2-p-methoxybenzyloxy-1-trimethylsilyloxy-but-3-enyl]-3,7-dimethyloct-3,6-dienoic acid methoxy-N-methyl-amide 
• 364337-27-9 (3R,4S,5S,6R)-4-[(E)-1,5-dimethyl-hex-1,4-dienyl]-6-p-methoxybenzyloxy-5-trimethylsilyloxy-1-oxaspiro[2.5]octane 
• 364337-24-6 (4S,5E)-4-[(1S,2R)-2-p-methoxybenzyloxy-1-trimethylsilyloxy-but-3-enyl]-5,9-dimethyl-deca-1,5,8-trienone 
• 364337-26-8 (2S,3S,4R)-2-[(E)-1,5-dimethyl-hex-1,4-dienyl]-4-p-methoxybenzyloxy-3-trimethylsilyloxy-cyclohexanone 
• 364337-22-4 (2S)-2-[(1S,2R)-1-hydroxy-2-p-methoxybenzyloxy-but-3-enyl]-3,7-dimethyloct-3,6-dienoic acid methoxy-N-methyl-amide 
• 364337-25-7 (4R,5S,6S)-4-p-methoxybenzyloxy-5-trimethylsilyloxy-6-[(E)-1,5-dimethyl-hex-1,4-dienyl]-cyclohex-2-enone 
• 364337-28-0 (3R,4S,5S,6R)-4-[(E)-1,5-dimethyl-hex-1,4-dienyl]-5-hydroxy-6-p-methoxybenzyloxy-1-oxaspiro[2.5]octane 
• 364337-21-3 (4R)-4-benzyl-3-{(2S)-2-[(1S,2R)-1-hydroxy-2-p-methoxybenzyloxy-but-3-enyl]-3,7-dimethyloct-3,6-dienoyl}-oxazolidin-2-one 

Relevant articles and documents

A new, ring closing metathesis-based synthesis of (-)-fumagillol

(Equation presented) A new strategy to access the fumagillin/fumagillol skeleton is proposed. An Evans aldolization and a RCM involving an enone are used for the preparation of a key cyclohexanone intermediate, which was readily converted to fumagillol. The synthesis also features an efficient preparation of isogeraniol and isogeranic acid.