105466-41-9

Basic information

• Product Name: RARECHEM AL BD 0944
• Synonyms: RARECHEM AL BD 0944;5-CHLORO-1,3-DIMETHYL-1H-PYRAZOLE-4-METHANOL;UKRORGSYN-BB BBV-5098331
• CAS NO: 105466-41-9
• Molecular Weight: 160.603
• Mol File: 105466-41-9.mol

Chemical Properties

• CAS DataBase Reference: RARECHEM AL BD 0944(CAS DataBase Reference)
• NIST Chemistry Reference: RARECHEM AL BD 0944(105466-41-9)
• EPA Substance Registry System: RARECHEM AL BD 0944(105466-41-9)

Safety Data

• Hazardous Substances Data: 105466-41-9(Hazardous Substances Data)

Upstream product

• 27006-83-3 1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride 
• 27006-76-4 5-chloro-4-formyl-1,3-dimethylpyrazole 

Downstream Products

• 1225381-98-5 5-chloro-1,3-dimethyl-4-[(2-methoxyphenyl)thiomethyl]-1H-pyrazole 
• 1183800-42-1 5-chloro-1,3-dimethyl-4-[(4-methoxyphenyl)thiomethyl]-1H-pyrazole 
• 1179741-64-0 5-chloro-1,3-dimethyl-4-(phenylthiomethyl)-1H-pyrazole 

Relevant articles and documents

SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS

The present invention is directed to substituted pyridizinone compounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

SUBSTITUTED PYRIDIZINONE DERIVATIVES AS PDE10 INHIBITORS

The present invention is directed to substituted pyridizinone compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.

OXIME ETHER COMPOUND AND AGRICULTURAL OR HORTICULTURAL BACTERICIDE

An oxime ether compound represented by the formula [I] or a salt thereof which have excellent bactericidal activity and are useful as an agricultural or horticultural fungicide. [I] (In the formula, R1 represents halogeno, hydroxy, C1-6 alkyl, C1-6 haloalkyl, C1-6 alkoxy, C1-6 alkyl substituted by C1-6 alkoxy, cyano, nitro, C2-6 alkenyl, C2-6 haloalkenyl, C2-6 alkynyl, amino, mono(C1-6 alkyl)amino, di(C1-6 alkyl)amino, C3-6 cycloalkyl, carboxyl, C1-6 alkoxycarbonyl, etc.; R2 represents hydrogen, C1-6 alkyl, C3-6 cycloalkyl, C1-6 haloalkyl, etc.; R3 and R4 each represents hydrogen or C1-6 alkyl; k is an integer of 1 to 4; and A represents the heterocyclic group shown in the description.)