1054786-40-1

Basic information

• Product Name: C₅₇H₆₁Cl₆NO₁₇
• Synonyms: C₅₇H₆₁Cl₆NO₁₇
• CAS NO: 1054786-40-1
• Molecular Weight: 1244.83
• Mol File: 1054786-40-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₇H₆₁Cl₆NO₁₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₇H₆₁Cl₆NO₁₇(1054786-40-1)
• EPA Substance Registry System: C₅₇H₆₁Cl₆NO₁₇(1054786-40-1)

Safety Data

• Hazardous Substances Data: 1054786-40-1(Hazardous Substances Data)

Upstream product

• 155396-69-3 (2R,4S,5R)-(2R,4S,5R)-3-tert-butoxycarbonyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid 
• 153652-73-4 (2R,4S,5R)-3-t-butoxycarbonyl-4-phenyl-2-(4-methoxyphenyl)-5-methoxycarbonyl-1,3-oxazolidine 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 124605-42-1 methyl (2R,3S)-3-(tert-butoxycarbonylamino)-2-hydroxy-3-phenylpropionate 

Downstream Products

• 114915-20-7 Docetaxel 

Relevant articles and documents

2-Monosubstituted-1,3-Oxazolidines as Improved Protective Groups of N-Boc-Phenylisoserine in Docetaxel Preparation

A new route for semisynthetic docetaxel, 1, is desribed using 2-monosubstituted-4-phenyl-1,3-oxazolidine-5-carboxylic acids in esterification of 7,10-O-diTroc-10-desacetylbaccatin III (4).Subsequent deprotection of esters 10(+10') afforded title compound 1 without removal of the Boc group.