105487-96-5

Downstream Products

• 134623-75-9 dl-trans-2-(4-methoxyphenyl)-2,3-dihydro-3-hydroxy-8-chloro-1,5-benzothiazepin-4(5H)-one 
• 96125-56-3 (-)-cis-2-(4-methoxyphenyl)-3-hydroxy-8-chloro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 

Relevant academic research and scientific papers

8-Chloro-1,5-benzothiazepine derivatives

Novel 8-chloro-1,5-benzothiazepine derivatives of the formula: STR1 wherein R1 is hydrogen, lower alkyl or a group of the formula: R4 CO--, each of R2 and R3 is lower alkyl and R4 is hydrogen or lower alkyl, and a pharmaceutically acceptable acid addition salt thereof are disclosed. Said derivative (I) and a pharmaceutically acceptable acid addition salt thereof are useful as hypotensive agents and/or coronary or cerebral vasodilators.

1,5-benzothiazepine derivatives and processes for preparing the same

Novel 1,5-benzothiazepine derivatives of the formula: STR1 wherein R 1 is hydrogen or lower alkyl, R 2 is hydrogen, lower alkanoyl or benzyl, R 3 is hydrogen or lower alkyl and either one of R 4 and R 5 is hydrogen and the other is chlorine, or a pharmace