105494-90-4

Basic information

• Product Name: Benzene, [(1-phenylpentyl)sulfonyl]-
• CAS NO: 105494-90-4
• Molecular Formula: C17H20O2S
• Molecular Weight: 288.411
• Mol File: 105494-90-4.mol

Chemical Properties

• CAS DataBase Reference: Benzene, [(1-phenylpentyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [(1-phenylpentyl)sulfonyl]-(105494-90-4)
• EPA Substance Registry System: Benzene, [(1-phenylpentyl)sulfonyl]-(105494-90-4)

Safety Data

• Hazardous Substances Data: 105494-90-4(Hazardous Substances Data)

Upstream product

• 68602-14-2 <1-(phenylthio)pentyl>benzene 

Downstream Products

• 77815-48-6 1-phenyl-1-phenylthio-1-trimethylsilylpentane 
• 1009-14-9 phenyl butyl ketone 
• 105494-84-6 1-phenyl-1-phenylsulphonyl-1-trimethylsilylpentane 

Relevant articles and documents

The Synthesis of Ketones via α-Silyl Sulphides

α-Phenylthiosilanes (2) have been prepared by alkylation of the anion (4) derived from the 1-phenylthio-1-trimethylsilylalkane (1).These anions (4) have benn prepared by a variety of methods including, direct deprotonation of (1), displacement of a phenylthio group by lithium naphthalenide addition of an alkyl-lithium to 1-phenylthio-1-trimethylsilylethene (7), and transmetallation of a tributylstannyl moiety.The formation of an alkyl-lithium by reaction of lithium naphthalenide with a phenyl sulphide provided an additional route to (2) from bis(phenylthio)acetals (8).An alternative path to the α-phenylthiosilanes (2) was to reduce the corresponding α-phenylsulphonylsilane (15); these, in turn, being readily available from alkylation or silylation of α-sulphonyl anions.The α-phenylthiosilanes (2) were converted into the O-trimethylsilylphenylthioacetal (18) by the sila-Pummerer rearrangement, although this was complicated by vinyl sulphide (20) formation in certain cases.Subsequent hydrolysis of (18) and (20) gave the ketone (3).