77815-48-6

Basic information

• Product Name: 1-phenyl-1-phenylthio-1-trimethylsilylpentane
• Synonyms: 1-phenyl-1-phenylthio-1-trimethylsilylpentane
• CAS NO: 77815-48-6
• Molecular Weight: 328.594
• Mol File: 77815-48-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-phenyl-1-phenylthio-1-trimethylsilylpentane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-1-phenylthio-1-trimethylsilylpentane(77815-48-6)
• EPA Substance Registry System: 1-phenyl-1-phenylthio-1-trimethylsilylpentane(77815-48-6)

Safety Data

• Hazardous Substances Data: 77815-48-6(Hazardous Substances Data)

Upstream product

• 91787-22-3 phenyl(phenylsulphonyl)trimethylsilylmethane 
• 105494-90-4 C₁₇H₂₀O₂S 
• 68602-14-2 <1-(phenylthio)pentyl>benzene 
• 100-39-0 benzyl bromide 
• 67274-35-5 trimethylsilane 
• 930-69-8 sodium thiophenolate 
• 3112-88-7 Benzyl phenyl sulfone 
• 831-91-4 Benzyl phenyl sulfide 
• 105494-84-6 1-phenyl-1-phenylsulphonyl-1-trimethylsilylpentane 
• 542-69-8 1-iodo-butane 
• 75-77-4 chloro-trimethyl-silane 
• 77815-76-0 1,1-bis(phenylthio)-1-phenylpentane 
• 109-65-9 1-bromo-butane 

Downstream Products

• 1009-14-9 phenyl butyl ketone 

Relevant articles and documents

The Synthesis of Ketones via α-Silyl Sulphides

α-Phenylthiosilanes (2) have been prepared by alkylation of the anion (4) derived from the 1-phenylthio-1-trimethylsilylalkane (1).These anions (4) have benn prepared by a variety of methods including, direct deprotonation of (1), displacement of a phenylthio group by lithium naphthalenide addition of an alkyl-lithium to 1-phenylthio-1-trimethylsilylethene (7), and transmetallation of a tributylstannyl moiety.The formation of an alkyl-lithium by reaction of lithium naphthalenide with a phenyl sulphide provided an additional route to (2) from bis(phenylthio)acetals (8).An alternative path to the α-phenylthiosilanes (2) was to reduce the corresponding α-phenylsulphonylsilane (15); these, in turn, being readily available from alkylation or silylation of α-sulphonyl anions.The α-phenylthiosilanes (2) were converted into the O-trimethylsilylphenylthioacetal (18) by the sila-Pummerer rearrangement, although this was complicated by vinyl sulphide (20) formation in certain cases.Subsequent hydrolysis of (18) and (20) gave the ketone (3).