1055070-43-3Relevant academic research and scientific papers
NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS
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Page/Page column 85, (2009/10/01)
The present application describes nitrogen containing heteroaromatics and derivatives thereof of formula (I) or pharmaceutically acceptable salt or prodrug forms thereof, wherein J is N or NH and D may be C(=NH)NH2, which are useful as inhibitors of factor Xa.
Pyrazole inhibitors of coactivator associated arginine methyltransferase 1 (CARM1)
Purandare, Ashok V.,Chen, Zhong,Huynh, Tram,Pang, Suhong,Geng, Jieping,Vaccaro, Wayne,Poss, Michael A.,Oconnell, Jonathan,Nowak, Kimberly,Jayaraman, Lata
supporting information; scheme or table, p. 4438 - 4441 (2009/04/06)
This study reports the identification and Hits to Leads optimization of inhibitors of coactivator associated arginine methyltransferase (CARM1). Compound 7b is a potent, selective inhibitor of CARM1.
