1055244-89-7Relevant academic research and scientific papers
Synthesis and structure-affinity relationships of novel spirocyclic σ receptor ligands with furopyrazole structure
Schlaeger, Torsten,Schepmann, Dirk,Wuerthwein, Ernst-Ulrich,Wuensch, Bernhard
, p. 2992 - 3001 (2008/09/20)
The synthesis of novel spirocyclic σ receptor ligands with high affinity is described. The cyclization of the hydroxy acetal 8, which represents a key step in the synthesis of the spirocyclic compounds 3, was supported by theoretical considerations. The a
Spiro-pyrano-pyrazole derivatives
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Page/Page column 13; 19, (2008/12/04)
The present invention relates to compounds of formula (I) having pharmacological activity towards the sigma (σ) receptor, and more particularly to some spiro-pyrano-pyrazole derivatives, to processes of preparation of such compounds, to pharmaceutical com
