1055335-23-3

Basic information

• Product Name: benzyl 2-deoxy-2-(2,2,2-trichloroethoxy)carbonylamino-β-D-glucopyranoside
• Synonyms: benzyl 2-deoxy-2-(2,2,2-trichloroethoxy)carbonylamino-β-D-glucopyranoside
• CAS NO: 1055335-23-3
• Molecular Weight: 444.696
• Mol File: 1055335-23-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: benzyl 2-deoxy-2-(2,2,2-trichloroethoxy)carbonylamino-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-deoxy-2-(2,2,2-trichloroethoxy)carbonylamino-β-D-glucopyranoside(1055335-23-3)
• EPA Substance Registry System: benzyl 2-deoxy-2-(2,2,2-trichloroethoxy)carbonylamino-β-D-glucopyranoside(1055335-23-3)

Safety Data

• Hazardous Substances Data: 1055335-23-3(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 187022-49-7 (2R,3S,4R,5R,6S)-2-(acetoxymethyl)-6-(phenylthio)-5-(((2,2,2-trichloroethoxy)carbonyl)amino)tetrahydro-2H-pyran-3,4-diyl diacetate 
• 133940-44-0 benzyl 3,4,6-tri-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranoside 

Downstream Products

• 1055335-26-6 benzyl 2-deoxy-2-trichloroethylcarbamoyl-6-O-(2,3,4-tri-O-benzyl-6-deoxy-α-L-galactosyl)-β-D-glucopyranoside 
• 206751-91-9 benzyl 2-acetamido-2-deoxy-3,6-di-O-pivaloyl-β-D-glucopyranoside 

Relevant articles and documents

Chemical synthesis of 4-azido-β-galactosamine derivatives for inhibitors of N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

Chondroitin sulfate E (CS-E) plays a crucial role in diverse processes ranging from viral infection to neuroregeneration. Its regiospecific sulfation pattern, generated by N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST), is the main structural determinant of its biological activity. Inhibitors of GalNAc4S-6ST can serve as powerful tools for understanding physiological functions of CS-E and its potential therapeutic leads for human diseases. A family of new 4-acylamino-β-GalNAc derivatives and 4-azido-β-GalNAc derivatives were synthesized for their potential application as inhibitors of GalNAc4S-6ST. The target compounds were evaluated for their inhibitory activities against GalNAc4S-6ST. The results revealed that 4-pivaloylamino- and 4-azido-β-GalNAc derivatives displayed evident activities against GalNAc4S-6ST with IC50 value ranging from 0.800 to 0.828?mM. They showed higher activities than benzyl D-GalNAc4S that was used as control.