105544-36-3

Usage

Uses

Used in Pharmaceutical Industry:
7-BROMO-1H-PYRIDO[2,3-B][1,4]OXAZIN-2(3H)-ONE is used as a building block for the synthesis of various organic compounds, particularly in the development of new pharmaceuticals. Its unique structure allows for the creation of diverse chemical products with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 7-BROMO-1H-PYRIDO[2,3-B][1,4]OXAZIN-2(3H)-ONE serves as a key intermediate in the synthesis of compounds with potential applications in agriculture, such as pesticides and herbicides.
Used in Antiviral and Antibacterial Applications:
7-BROMO-1H-PYRIDO[2,3-B][1,4]OXAZIN-2(3H)-ONE has been studied for its potential biological activities, particularly as an antiviral and antibacterial agent. Its unique structure may contribute to the development of new treatments for viral and bacterial infections.

Upstream product

• 105544-30-7 ethyl-2-((5-bromo-3-nitropyridin-2-yl)oxy)acetate 
• 227963-72-6 methyl 2-((5-bromo-3-nitropyridin-2-yl)oxy)acetate 
• 67443-38-3 5-bromo-2-chloro-3-nitropyridine 

Downstream Products

• 946121-78-4 7-bromo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine 
• 615568-51-9 2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-7-carbaldehyde 
• 1349831-01-1 7-((2R,5R)-2-methyl-5-phenylmorpholino)-1H-pyrido[2,3-b]-[1,4]oxazin-2(3H)-one 
• 1313439-65-4 6-(4-(1-aminocyclobutyl)phenyl)-7-(cyclopropylmethyl)-1-methyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one 
• 1313441-62-1 tert-butyl (1-(4-(7-(cyclopropylmethyl)-1-methyl-2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 
• 1313441-61-0 tert-butyl (1-(4-(7-allyl-1-methyl-2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 
• 1313441-60-9 tert-butyl (1-(4-(7-(4-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 
• 1313439-58-5 6-(4-(1-aminocyclobutyl)phenyl)-1-methyl-7-(thiophen-2-yl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one 
• 1313441-52-9 tert-butyl (1-(4-(1-methyl-2-oxo-7-(thiophen-2-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 
• 1313439-57-4 6-(4-(1-aminocyclobutyl)phenyl)-1-methyl-7-(thiophen-3-yl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one 
• 1313441-51-8 tert-butyl (1-(4-(1-methyl-2-oxo-7-(thiophen-3-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 
• 1313439-56-3 6-(4-(1-aminocyclobutyl)phenyl)-1-methyl-7-(pyridin-3-yl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one 
• 1313441-50-7 tert-butyl (1-(4-(1-methyl-2-oxo-7-(pyridin-3-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 
• 1313441-49-4 tert-butyl (1-(4-(7-bromo-1-methyl-2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutyl)carbamate 

Relevant academic research and scientific papers

CHROMENOPYRIMIDINE DERIVATIVES AS PHOSPHATIDYLINSITOL PHOSPHATE KINASE INHIBITORS

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula: where A1, A2, G, R1, R2, R3, R4, and W are described herein.

AMINOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula: (I) where A, B, R1, X1, X2, and W are described herein.

HETEROARYL COMPOUNDS AS INHIBITORS OF NECROSIS, COMPOSITION AND METHOD USING THE SAME

The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis. Formula (I) is shown below:

Short and efficient synthesis of oxazinone-and thiazinone-containing bicyclic heteroaromatic aldehydes

Short and efficient route for the synthesis of oxazinone-and thiazinone-containing bicyclic heteroaromatic aldehydes, which involves the key step of palladium-catalyzed reductive carbonylation, is described. Overall routes for the synthesis of these aldehydes are short, versatile, and scalable with good yields of the product. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]

HETEROCYCLIC DERIVATIVES

The present invention relates to heterocyclic derivatives, and more particularly, to novel heterocyclic derivatives useful for the preparation of medicaments for treating diseases related to uric acid.

Novel bicyclic sulfonamide derivatives which are L-CPT1 inhibitors

The invention is concerned with novel heterobicyclic derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, V, W, X and Y are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.

FUSED HETEROCYCLIC COMPOUND AND USE THEREOF

The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineral corticoidreceptorantagonistic action and is useful as an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like, a compound having a fused heterocycle, or a prodrug thereof, or a salt thereof; and an agent for the prophylaxis or treatment of hypertension, cardiac failure and the like.