105550-85-4Relevant academic research and scientific papers
An Efficient Method for the Preparation of 2-Thioxotetrahydro-1,3-oxazines
Fueloep, Ferenc,Csirinyi, Gyoergy,Bernath, Gabor,Szabo, Jozsef A.
, p. 1149 - 1151 (2007/10/02)
2-Thioxotetrahydro-1,3-oxazole and 2-thioxotetrahydro-1,3-oxazines (including cycloalkane-fused derivatives) are prepared by reaction of 2- or 3-aminoalkanols, respectively, with carbon disulfide and triethylamine and condensation of the triethylammonium dithiocarbamates thus obtained with ethyl carbonochloridate and triethylamine.The yields of the 2-thioxo-1,3-O,N-heterocycles thus prepared are considerably higher than those obtained by the earlier methods.
