105558-72-3Relevant academic research and scientific papers
Basic Ionic Liquid [bmIm]OH-Mediated Gewald Reaction as Green Protocol for the Synthesis of 2-Aminothiophenes
Kaki, Venkata Rao,Akkinepalli, Raghuram Rao,Deb, Pran Kishore,Pichika, Mallikarjuna Rao
, p. 119 - 126 (2015/10/20)
A simple, efficient, and environmental friendly procedure was developed based on the Gewald reaction for the synthesis of 2-aminothiophenes using a basic ionic liquid [bmIm]OH as both catalyst and solvent. Besides being a green protocol, the method offers advantages of successful synthesis of a variety of alkyl, aryl, alkoxy, and alkylamino-2-aminothiophenes in good yields.
Transesterification of trimethyl orthoacetate: An efficient protocol for the synthesis of 4-alkoxy-2-aminothiophene-3-carbonitriles
Venkata Rao,Balakumar,Lakshmi Narayana,Pran Kishore,Rajwinder,Raghuram Rao
supporting information, p. 1274 - 1278 (2013/03/13)
A facile one-pot method is reported for the synthesis of 4-alkoxy-2-aminothiophene-3-carbonitriles. Transesterification of trimethylorthoacetate technique allowed introducing alkoxy substituents into 2-aminothiophene ring system. Diverse alkoxy substituents could be introduced efficiently by using this methodology. Further the synthesis of some of new 4-alkylamino-2-aminothiophenes is also reported.
Thiophene derivatives
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, (2008/06/13)
The novel compound of the general formula I STR1 where X is fluorine, chlorine, bromine, SO2 Y or unsubstituted or substituted hydroxyl or mercapto, Y is alkyl, alkenyl, cycloalkyl, aralkyl, aryl, chlorine or unsubstituted or substituted hydrox
