99580-50-4

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
2-Amino-3-cyano-4-hydroxythiophene serves as a key building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure and functional groups contribute to the development of new drugs and pesticides with improved efficacy and selectivity.
Used in Organic Synthesis:
As a versatile reagent in organic synthesis, 2-Amino-3-cyano-4-hydroxythiophene is utilized in various chemical reactions to form a wide range of organic compounds. Its presence in these reactions allows for the creation of diverse molecular structures with potential applications in various industries.
Used in Material Science:
2-Amino-3-cyano-4-hydroxythiophene has been studied for its potential applications in material science. Its unique properties, such as its ability to form stable complexes and its electronic characteristics, make it a promising candidate for the development of new materials with specific properties.
Used as a Precursor for Organic Semiconductors:
In the field of organic semiconductors, 2-Amino-3-cyano-4-hydroxythiophene is recognized as a valuable precursor for the synthesis of novel semiconductor materials. These materials have potential applications in electronic devices, such as organic light-emitting diodes (OLEDs) and organic solar cells, due to their tunable electronic properties and processability.
Used in Antitumor and Antimicrobial Applications:
2-Amino-3-cyano-4-hydroxythiophene exhibits potential biological activities, such as antitumor and antimicrobial properties. Its ability to interact with biological targets and disrupt essential cellular processes makes it a promising candidate for the development of new therapeutic agents against cancer and infectious diseases.

Upstream product

• 1445-45-0 Trimethyl orthoacetate 
• 105558-72-3 2-amino-4-ethoxythiophene-3-carbonitrile 
• 79-04-9 chloroacetyl chloride 
• 109-77-3 malononitrile 

Downstream Products

• 137240-10-9 4,5-dichlorothieno[2,3-d]pyrimidine 

Relevant academic research and scientific papers

Thienopyrimidine compound and medical applications thereof

The present invention relates to a thienopyrimidine-containing compound represented by a general formula (I), a pharmaceutically acceptable salt, a solvate and a prodrug thereof, wherein the substituents R1, R2, R3, R4, R5 and Q are defined in the specifi

Basic Ionic Liquid [bmIm]OH-Mediated Gewald Reaction as Green Protocol for the Synthesis of 2-Aminothiophenes

A simple, efficient, and environmental friendly procedure was developed based on the Gewald reaction for the synthesis of 2-aminothiophenes using a basic ionic liquid [bmIm]OH as both catalyst and solvent. Besides being a green protocol, the method offers advantages of successful synthesis of a variety of alkyl, aryl, alkoxy, and alkylamino-2-aminothiophenes in good yields.

Thiophene derivatives

The novel compound of the general formula I STR1 where X is fluorine, chlorine, bromine, SO2 Y or unsubstituted or substituted hydroxyl or mercapto, Y is alkyl, alkenyl, cycloalkyl, aralkyl, aryl, chlorine or unsubstituted or substituted hydrox

Trialkylamine salts of 3-chloro-1,1-dicyano-2-hydroxy-1-propene and preparation of 2-amino-4-chloro-3-cyano-5-formylthiophene

Trialkylamine salts of 3-chloro-1,1-dicyano-2-hydroxy-1-propene, where the trialkylamine has from 10 to 24 carbon atoms, a process for their preparation from malononitrile, chloroacetyl chloride, and a trialkylamine, and a process for the preparation of 2-amino-4-chloro-3-cyano-5-formylthiophene in which a trialkylamine salt of 3-chloro-1,1-dicyano-2-hydroxy-1-propene is cyclized with hydrogen sulfide or another sulfide and treated with a mixture of N,N-dimethylformamide and phosphoryl chloride, and the product is hydrolyzed by acid without being isolated previously.

Preparation of aminothiophene derivatives

Abstract of the Disclosure: Aminothiophene derivatives of the formula I STR1 where R is unsubstituted or substituted C1 -C8 -alkyoxycarbonyl, unsubstituted or substituted carbamyl or cyano, are prepared by a process in which a compound of the formula II where R has the above meanings, is reacted in water with a base and simultaneously or subsequently with a haloacetyl halide, and the product is then reacted with hydrogen sulfide or a water-soluble sulfide.