105575-94-8Relevant academic research and scientific papers
Five- and six-membered cyclic α-acylvinyl anionic synthons: Synthesis of α-trimethylsilyl-α,β-unsaturated cycloalkenones and their conversion into 2-(hydroxydimethylsilyl)cycloalk-2-enones through carbon-silicon bond scission
Jyothi, Divya,Suresh, Hariprasad
, p. 194 - 203 (2012/05/20)
Five- and six-membered α-trimethylsilyl-α,β-unsaturated cycloalkenones were prepared by the Wurtz-Fittig coupling reaction of the corresponding 6-bromo-1,4-dioxaspiro[4,n]cycloalk-6-enes with sodium and chlorotrimethylsilane. Upon treatment with anhydrous
Cyclic α-acylvinyl anionic synthons: A novel synthesis of 2-trimethylsilyl-3-methyl-cyclohexenone by the Wurtz-Fittig coupling reaction
Jyothi, Divya,HariPrasad
experimental part, p. 875 - 879 (2009/09/05)
2-Trimethylsilyl-3-methyl-cyclohexen-1-one: a cyclic α-acyl anionic synthon was prepared in good yield by the Wurtz-Fittig coupling reaction of 6-bromo-7-methyl-1,4-dioxaspiro[4,5]-6-decene with metallic sodium and chlorotrimethylsilane in anhydrous ether solvent. Copyright Taylor & Francis Group, LLC.
A NOVEL SYNTHESIS OF CYCLOPENTENONES AND CYCLOHEXENONES VIA CYCLIACYLATION OF LITHIOALKENYLCARBOXAMIDES
Sawada, Hiroyuki,Webb, Michael,Stoll, A. Timothy,Negishi, Ei-ichi
, p. 775 - 778 (2007/10/02)
The reaction of 1-iodo-3-bromopropene derivatives (1) with lithium enolates of N,N-dialkylcarboxamides followed by treatment of the allylation product (2) with two equiv of t-BuLi cleanly provides cyclopentenones in high yields, while the corresponding cycliacylation reaction of 6-iodo-5-hexenamides provides cyclohexenones.
