1055971-28-2

Upstream product

• 4101-30-8 2-amino-4,5-dimethoxyacetophenone 

Downstream Products

• 1055964-32-3 2-(5-{3-[benzyl(methyl)amino]prop-1-yn-1-yl}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine 
• 1055964-36-7 2-{5-[⁽³⁵⁾-3-amino-4-phenylbut-1-yn-1-yl]pyridin-3-yl}-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine 
• 1055969-37-3 {3-[5-(4-amino-8,9-dimethoxy-benzo[c][2,7]naphthyridin-2-yl)-pyridin-3-yl]-1-benzyl-prop-2-ynyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

BENZO[C][2,7]NAPHTHYRIDINE DERIVATIVES, AND THEIR USE AS KINASE INHIBITORS

The present invention relates to Benzo[c] [2,7] naph thy ri dine Derivatives of formula (I), compositions comprising an effective amount of a Benzo[c] [2,7]naphthyridine Derivative, methods for treating or preventing a proliferative disorder or an autoimmune disease, comprising administering to a subject in need thereof an effective amount of a Benzo[c] [2,7]naphthyridine Derivative, methods for modulating PDK-I activity, PKA activity, Akt activity, S6K activity, or PKC activity, comprising administering to a subject in need thereof an effective amount of a Benzo[c] [2,7] naphthyridine Derivative. The invention also relates to processes for preparing a Benzo[c] [2,7] naphthyridine Derivative.