1055981-47-9Relevant academic research and scientific papers
Cascade enantioselective synthesis of 3-arylphthalides using chiral auxiliary route
Karnik, Anil V.,Katnath, Suchitra S.
, p. 1832 - 1834 (2008)
An enantioselective synthesis of 3-arylphthalides was achieved using (S)-1-phenylethylamine as a chiral auxiliary. Reduction of chiral keto amides of 2-aroylbenzoic acids followed by acid-catalyzed lactonization yielded (S)-3-arylphthalides with 75-85% ee.
