1056159-19-3

Upstream product

• 1692-15-5 4-pyridylboronic acid 
• 136434-77-0 4-bromo-3-fluoroiodobenzene 

Downstream Products

• 872508-17-3 ethyl (3S)-1-(2-fluoro-4-pyridin-4-ylphenyl)piperidine-3-carboxylate 
• 1231191-74-4 4-(4-ethynyl-3-fluorophenyl)pyridine 

Relevant academic research and scientific papers

TRIAZOLE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE

According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of A?42 and hence are useful in treatment of Alzheimer's disease and related conditions.

N-substituted piperidines and their use as pharrmaceuticals

The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-β hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.