105627-80-3 Usage
Uses
Used in Pharmaceutical Industry:
1-Chloro-5-isoquinolinesulfonic Acid is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique chemical structure allows it to be a versatile component in the synthesis of drugs targeting different medical conditions.
Used in Organic Synthesis:
1-Chloro-5-isoquinolinesulfonic Acid is used as a key building block in organic synthesis for creating a wide range of organic molecules. Its reactivity and functional groups make it suitable for various chemical reactions, leading to the formation of complex molecules with diverse applications.
Used in Chemical Research:
1-Chloro-5-isoquinolinesulfonic Acid is also employed as a research compound in the field of chemistry. It is used to study various chemical reactions and mechanisms, contributing to the advancement of knowledge in organic chemistry and related disciplines.
Check Digit Verification of cas no
The CAS Registry Mumber 105627-80-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,6,2 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 105627-80:
(8*1)+(7*0)+(6*5)+(5*6)+(4*2)+(3*7)+(2*8)+(1*0)=113
113 % 10 = 3
So 105627-80-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H6ClNO3S/c10-9-7-2-1-3-8(15(12,13)14)6(7)4-5-11-9/h1-5H,(H,12,13,14)
105627-80-3Relevant academic research and scientific papers
Isoquinolines as urokinase inhibitors
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, (2008/06/13)
Compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is H and the other is N=C(NH2)2 or NHC(=NH)NH2, and the other substituents are as defined herein, are urokinase (uPA) inhibitors.
Substituted isoquinolinesulfonyl compounds
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, (2008/06/13)
An isoquinolinesulfonyl compound represented by the formula (I): STR1 wherein R1 : H, Cl, OH A : unsubstituted or substituted ethylene or alkylene R2, R3 : H, alkyl, jointly forming unsubstituted or substituted ethylene or trimethylene R4 : H, alkyl, amidino or an acid salt thereof. They can be prepared, for example, by converting 1-R1 substituted-5-isoquinolinesulfonic acid to the corresponding sulfonyl chloride and subsequently reacting the chloride with a compound of formula STR2 They can be advantageously utilized as vasodilator, cerebral circulation ameliorator, antihypertensive agent and drugs for prevention and treatment of various circulatory organ diseases.