105628-63-5

Basic information

• Product Name: (2-AMINO-ETHYL)-ETHYL-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: tert-butyl 2-aminoethyl(ethyl)carbamate;Carbamic acid,N-(2-aminoethyl)-N-ethyl-, 1,1-dimethylethyl ester;Aminoethyl-ethylcarbamic acid tertbutyl ester;Ntbutylcxycarbonylnethylethylenediamine;tert-Butyl N-(2-aMinoethyl)ethylcarbaMate;2-(N-Boc-N-ethylaMino)ethylaMine;(2-AMinoethyl)ethyl-carbaMic Acid 1,1-DiMethylethyl Ester;(2-Aminoethyl)(ethyl)carbamic acid tert-butyl este
• CAS NO: 105628-63-5
• Molecular Formula: C₉H₂₀N₂O₂
• Molecular Weight: 188.27
• Product Categories: Amines;Miscellaneous Reagents
• Mol File: 105628-63-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 253℃
• Flash Point: 107℃
• Appearance: Protected ethylenediamine, used for ethylenediamine addition
• Density: 0.982
• Vapor Pressure: 0.0184mmHg at 25°C
• Refractive Index: 1.462
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.44±0.10(Predicted)
• CAS DataBase Reference: (2-AMINO-ETHYL)-ETHYL-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-ETHYL)-ETHYL-CARBAMIC ACID TERT-BUTYL ESTER(105628-63-5)
• EPA Substance Registry System: (2-AMINO-ETHYL)-ETHYL-CARBAMIC ACID TERT-BUTYL ESTER(105628-63-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 105628-63-5(Hazardous Substances Data)

Usage

Chemical Properties

tert-Butyl (2-aminoethyl)(ethyl)carbamate is White crystalline powder

Uses

Different sources of media describe the Uses of 105628-63-5 differently. You can refer to the following data:
1. Protected ethylenediamine, used for ethylenediamine addition.
2. tert-Butyl (2-aminoethyl)(ethyl)carbamate used for ethylenediamine addition.

InChI:InChI=1/C9H20N2O2/c1-5-11(7-6-10)8(12)13-9(2,3)4/h5-7,10H2,1-4H3

Upstream product

• 110-72-5 N-ethylethane-1,2-diamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 108-98-5 thiophenol 
• 152192-95-5 tert-butyl N-ethyl-N-(2-hydroxyethyl)carbamate 
• 152192-97-7 N₁-tert-butoxycarbonyl-N₁-ethyl-N₂-phthalyl-1,2-ethanediamine 

Downstream Products

• 1190896-17-3 N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-{2-[(tert-butoxycarbonyl)(ethyl)amino]ethyl}glycinamide 
• 1190893-66-3 N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-{2-[(tert-butoxycarbonyl)(ethyl)amino]ethyl}glycinamide 
• 1051928-37-0 tert-butyl ethyl(2-(3-(5-(2-methoxybenzylcarbamoyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzylamino)ethyl)carbamate 

Relevant articles and documents

Development of an Intein-Inspired Amide Cleavage Chemical Device

A photoresponsive amide cleavage device was developed based on the asparagine imidation-mediated cleavage of peptide bonds during intein-mediated protein splicing. The chemical environment of the protein splicing process was mimicked by the incorporation of geminal dimethyl groups and a secondary amine unit in asparagine scaffold. Furthermore, the resulting photoresponsive device could induce the phototriggered cleavage of an amide bond by the protection of the secondary amine unit with an o-nitrobenzyloxycarbonyl group.

Compounds

Pyrimidone compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in treating atherosclerosis.

Preparation of mono Boc-protected unsymmetrical diamines

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