1056474-07-7

Usage

Uses

Used in Pharmaceutical Synthesis:
(E)-1,4-dimethyl-2-(2-nitrovinyl)benzene is used as a precursor in the pharmaceutical industry for the synthesis of various pharmaceuticals and organic compounds. Its unique structure allows it to be a key component in the development of new drugs and medications.
Used in Polymer and Plastics Production:
In the polymer and plastics industry, (E)-1,4-dimethyl-2-(2-nitrovinyl)benzene is utilized in the production of polymers and plastics. Its ability to undergo polymerization makes it a valuable asset in creating a wide range of materials with diverse applications.
Used in Dyes and Pigments Manufacturing:
(E)-1,4-dimethyl-2-(2-nitrovinyl)benzene is also employed as an intermediate in the manufacturing of dyes, pigments, and fragrance compounds. Its chemical properties contribute to the development of vibrant and stable colorants for various industries.
Used in Organic Synthesis and Research Laboratories:
(E)-1,4-dimethyl-2-(2-nitrovinyl)benzene is a valuable building block in organic synthesis and research laboratories. Its versatility in chemical reactions makes it an essential tool for scientists and researchers working on the development of new chemical compounds and materials.

Upstream product

• 2039-89-6 2,5-dimethylstyrene 

Downstream Products

• 23068-44-2 2-(2,5-dimethylphenyl)ethylamine 

Relevant academic research and scientific papers

Metal-free, room temperature, acid-K2S2O8 mediated method for the nitration of olefins: An easy approach for the synthesis of nitroolefins

Here, we have developed a simple, room temperature method for the nitration of olefins by using inexpensive sodium nitrite as a source of nitro groups in the presence of trifluoroacetic acid (TFA) and potassium persulfate (K2S2O8) under an open atmosphere. Styrenes and mono-substituted olefins give stereo-selective corresponding E-nitroolefins under optimized conditions, however, 1,1-bisubstituted olefins give a mixture of E- and Z-nitroolefins. The optimized conditions work well with electron-donating, electron-withdrawing, un-substituted and heterocyclic styrenes and mono-substituted olefins and give corresponding nitroolefins with good to excellent yields.

Method for catalytically synthesizing (E)-beta-nitrostyrene derivatives based on tetraarylporphyrin iron

The invention discloses a method for catalytically synthesizing (E)-beta-nitrostyrene derivatives based on tetraarylporphyrin iron. According to the method, styrene derivatives are subjected to one-pot reaction in a system containing tetraarylporphyrin iron (III), ammonium iodide and tert-butyl hydroperoxide to generate the (E)-beta-nitrostyrene derivatives. The method is capable of synthesizing beta-nitrostyrene derivatives with high E stereoselectivity with high yield under the mild reaction condition.

In order to iodide is one pot synthesis nitryl source α, β - unsaturated nitro olefin derivatives (by machine translation)

The present invention discloses a one-pot synthesis nitryl source iodide is α, β - unsaturated nitro olefin derivatives, vinyl compounds containing four aryl ferrous (III), iodide and tertiary-butyl hydrogen peroxide in acetonitrile solution system a pot of reaction, generating α, β - unsaturated nitro olefin derivatives; the method to achieve the under mild reaction conditions, high yield with high stereo selectivity of the E synthesis of α, β - unsaturated nitro olefin. (by machine translation)

Α, β - unsaturated nitro olefin derivative synthesis method (by machine translation)

The invention discloses a α, β - unsaturated nitro olefin derivative synthesis method, vinyl compounds containing four aryl ferrous (III), ammonium halide and tertiary-butyl hydrogen peroxide in the system of the one-pot reaction, generating α, β - unsaturated nitro olefin derivatives; the method to achieve the under mild reaction conditions, high yield with high stereo selectivity of the E synthesis of α, β - unsaturated nitro olefin. (by machine translation)

High-selectivity (E)-beta-nitrostyrene derivative one-pot synthesizing method

The invention discloses a high-selectivity (E)-beta-nitrostyrene derivative one-pot synthesizing method. In air or sealed environment, styrene derivative generates one-pot reaction in a system containing tetra-acryl ferroporphyrin (III), ammonium iodide and tert-butyl hydroperoxide to generate (E)-beta-nitrostyrene derivative. The method achieves the purpose of synthesizing the beta-nitrostyrene derivative with high E three-dimensional selectivity in high yield under moderate reaction conditions.

K2S2O8-mediated nitration of alkenes with NaNO2 and 2,2,6,6-tetramethylpiperidine-1-oxyl: Stereoselective synthesis of (E)-nitroalkenes

A transition-metal-free nitration of alkenes with NaNO2 in the presence of K2S2O8 and 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) is developed. The transformation exhibits a broad substrate scope and good functional group tolerance, thus providing a new and expedient protocol for stereoselective synthesis of (E)-nitroalkenes with moderate to good yields. Moreover, the nitration processes of (E)- and (Z)-stilbene are also studied: even though the proportion of substrates is different, the E/Z ratio of the products is basically the same. Based upon experimental observations, a possible reaction mechanism is proposed.