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benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside

    Cas No: 1056476-10-8

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  • benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside

    Cas No: 1056476-10-8

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  • Shangdong Shinning Pharm co.ltd
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  • 1056476-10-8 Structure
  • Basic information

    1. Product Name: benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside
    2. Synonyms: benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside
    3. CAS NO:1056476-10-8
    4. Molecular Formula:
    5. Molecular Weight: 1429.83
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1056476-10-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside(CAS DataBase Reference)
    10. NIST Chemistry Reference: benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside(1056476-10-8)
    11. EPA Substance Registry System: benzyl (3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,4-di-O-benzyl-6-O-tert-butyldimethylsilyl-α-D-mannopyranoside(1056476-10-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1056476-10-8(Hazardous Substances Data)

1056476-10-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1056476-10-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,6,4,7 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1056476-10:
(9*1)+(8*0)+(7*5)+(6*6)+(5*4)+(4*7)+(3*6)+(2*1)+(1*0)=148
148 % 10 = 8
So 1056476-10-8 is a valid CAS Registry Number.

1056476-10-8Downstream Products

1056476-10-8Relevant articles and documents

A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

Doores, Katie J.,Fulton, Zara,Hong, Vu,Patel, Mitul K.,Scanlan, Christopher N.,Wormald, Mark R.,Finn,Burton, Dennis R.,Wilson, Ian A.,Davis, Benjamin G.

scheme or table, p. 17107 - 17112 (2011/02/25)

Antibody 2G12 uniquely neutralizes a broad range of HIV-1 isolates by binding the high-mannose glycans on the HIV-1 surface glycoprotein, gp120. Antigens that resemble these natural epitopes of 2G12 would be highly desirable components for an HIV-1 vaccine. However, host-produced (self)-carbohydrate motifs have been unsuccessful so far at eliciting 2G12-like antibodies that cross-react with gp120. Based on the surprising observation that 2G12 binds nonproteinaceous monosaccharide D-fructose with higher affinity than D-mannose, we show here that a designed set of nonself, synthetic monosaccharides are potent antigens. When introduced to the terminus of the D1 arm of protein glycans recognized by 2G12, their antigenicity is significantly enhanced. Logical variation of these unnatural sugars pinpointed key modifications, and the molecular basis of this increased antigenicity was elucidated using high-resolution crystallographic analyses. Virus-like particle protein conjugates containing such nonself glycans are bound more tightly by 2G12. As immunogens they elicit higher titers of antibodies than those immunogenic conjugates containing the self D1 glycan motif. These antibodies generated from nonself immunogens also cross-react with this self motif, which is found in the glycan shield, when it is presented in a range of different conjugates and glycans. However, these antibodies did not bind this glycan motif when present on gp120.

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