105656-01-7

Upstream product

• 111275-60-6 1-O-(2-benzyloxycarbonylamino-2-deoxy-4:6-O-ethylidene-β-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 73446-41-0 3,4,6-tri-O-acetyl-2-(benzoyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl bromide 
• 111275-60-6 1-O-(2-benzyloxycarbonylamino-2-deoxy-4:6-O-ethylidene-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 99194-78-2 1-O-(3,4,6-tri-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 99194-79-3 1-O-(2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 111275-65-1 2,4,6-tri-O-acetyl-3-benzyloxycarbonylamino-3-deoxy-β-D-glucopyranose 
• 2783-43-9 Acetic acid (2R,3S,4S,5R,6R)-5-acetoxy-2-acetoxymethyl-4-benzyloxycarbonylamino-6-bromo-tetrahydro-pyran-3-yl ester 
• 99194-76-0 3,4,6-tri-O-acetyl-2-{[(benzyloxy)carbonyl]amino}-2-deoxy-β-D-glucopyranose 
• 99194-78-2 1-O-(3,4,6-tri-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 99194-79-3 1-O-(2-benzyloxycarbonylamino-2-deoxy-β-D-glucopyranosyl)-4'-O-benzyloxycarbonyl-4'-O-demethyl-1-epipodophyllotoxin 
• 131118-80-4 2-benzyloxycarbonylamino-1,3-di-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α/β-D-glucopyranose 
• 112146-44-8 2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranose 
• 112146-44-8 2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-αβ-D-glucopyranose 
• 131118-83-7 4'-O-benzyloxycarbonyl-4-O-(2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 

Downstream Products

• 111275-51-5 1-O-(2-chloroethylamino-2-deoxy-4:6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-1-epipodophyllotoxin 
• 105655-99-0 1-O-(2-dimethylamino-2-deoxy-4:6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-1-epipodophyllotoxin 
• 105655-99-0 4'-O-demethyl-4-O-(2-deoxy-2-dimethylamino-4,6-O-ethylidene-α-D-glucopyranosyl)-4-epipodophyllotoxin 
• 105655-99-0 4'-O-demethyl-4-O-(2-deoxy-2-dimethylamino-4,6-O-ethylidene-β-D-glucopyranosyl)-4-epipodophyllotoxin 

Relevant academic research and scientific papers

Etoposide: a new approach to the synthesis of 4-O-(2-amino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin

Synthesis of 3-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-4,6-O-ethylidene-α-(7α) and -β-D-glucopyranose (7β) and their 3-O-chloroacetyl analogues (11α and 11β) are described.Condensation (BF3-etherate, ethyl acetate, -20 deg C) of 7α with 4'-O-benzyloxyca