105740-20-3

Upstream product

• 112276-40-1 Methanesulfonic acid (R)-4-tert-butoxycarbonylamino-5-(3,4-dimethoxy-phenyl)-pentyl ester 
• 105811-46-9 (S)-2-(tert-butoxycarbonylamino)-3-(3,4-dimethoxyphenyl)-1-(4-methylbenzenesulfonyloxy)propane 
• 110469-82-4 [(R)-1-(3,4-Dimethoxy-benzyl)-4-iodo-butyl]-carbamic acid tert-butyl ester 
• 112276-39-8 (S)-4-(tert-butoxycarbonylamino)-5-(3,4-dimethoxyphenyl)-1-pentanol 
• 105779-71-3 (S)-(-)-[2-(3,4-dimethoxyphenyl)-1-hydroxymethylethyl]carbamic acid tert-butyl ester 
• 80582-39-4 (2S)-2-amino-3-(3,4-dimethoxyphenyl)-1-propanol 
• 105779-73-5 (2R)-1-(3,4-dimethoxyphenyl)-2-t-butoxycarbonylamino-6-cyano-6-(i-propyl)-6-(3,4-dimethoxyphenyl)hexane 
• 105740-21-4 (R)-2-(tert-butoxycarbonylamino)-1-(3,4-dimethoxyphenyl)-4-pentene 

Downstream Products

• 105740-25-8 (3S,7R)-7-formamido-3,8-di-(3,4-dimethoxyphenyl)-2-methyl-3-octanenitrile 
• 105740-26-9 (3R,7R)-7-formamido-3,8-di-(3,4-dimethoxyphenyl)-2-methyl-3-octanenitrile 
• 105740-32-7 (R)-3-<(S)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhex-1-yl>-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline 
• 112276-36-5 (R)-3-<(R)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhex-1-yl>-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline 
• 112276-31-0 (S)-5-((R)-6,7-Dimethoxy-3,4-dihydro-isoquinolin-3-yl)-2-(3,4-dimethoxy-phenyl)-2-isopropyl-pentanenitrile 
• 112276-31-0 (R)-5-((R)-6,7-Dimethoxy-3,4-dihydro-isoquinolin-3-yl)-2-(3,4-dimethoxy-phenyl)-2-isopropyl-pentanenitrile 
• 110469-83-5 (S)-2-(3,4-Dimethoxy-phenyl)-5-((R)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-2-isopropyl-pentanenitrile 
• 110469-83-5 (R)-2-(3,4-Dimethoxy-phenyl)-5-((R)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-2-isopropyl-pentanenitrile 

Relevant academic research and scientific papers

SYNTHESIS AND DETERMINATION OF THE ABSOLUTE STEREOCHEMISTRY OF THE ENANTIOMERS OF 3-SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINES RELATED TO THE CALCIUM ANTAGONIST VERAPAMIL

The four stereoisomers of 3--1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline (2) were prepared.The stereochemistry of the side chain quaternary carbon was derived from iodide 4 of known absolute conf