1057855-29-4

Basic information

• Product Name: N-[2-({[(5-chloropyridin-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
• Synonyms: N-[2-({[(5-chloropyridin-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
• CAS NO: 1057855-29-4
• Molecular Weight: 441.941
• Mol File: 1057855-29-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[2-({[(5-chloropyridin-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[2-({[(5-chloropyridin-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide(1057855-29-4)
• EPA Substance Registry System: N-[2-({[(5-chloropyridin-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide(1057855-29-4)

Safety Data

• Hazardous Substances Data: 1057855-29-4(Hazardous Substances Data)

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 40473-01-6 2-Bromo-5-chloro-pyridine 
• 86873-60-1 5-chloropicolinic acid 
• 163423-99-2 tert-butyl (2-nitrobenzyl)carbamate 
• 1057651-77-0 C₂₀H₂₆N₄O₃S 
• 24835-08-3 2-nitrobenzylamine hydrochloride 
• 162046-50-6 tert-butyl 2-aminobenzylcarbamate 

Downstream Products

• 1286182-11-3 N-[2-({[(5-chloropyridin-2-yl)carbonyl]amino}methyl)phenyl]-5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carboxamide hydrochloride 

Relevant articles and documents

2-Aminomethylphenylamine as a novel scaffold for factor Xa inhibitor

We have been researching orally active factor Xa inhibitor for a long time. We explored the new diamine linker using effective ligands to obtain a new attractive original scaffold 2-aminomethylphenylamine derivative. Compound 1D showed very strong in vitro and in vivo factor Xa inhibitory activity, as well as favorable PK profiles in po administration to monkeys.