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"16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one" is a complex organic compound with a molecular formula of C27H38O2. It is a derivative of the naturally occurring steroid hormone androstane, featuring a 4-methoxy-benzylidene group attached at the 16th carbon position. 16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one is characterized by its unique structure, which includes a 5α-configuration and a 3β-hydroxyl group, as well as a ketone group at the 17th carbon position. It is known for its potential applications in the field of medicine and pharmaceuticals, particularly in the development of drugs targeting hormonal imbalances and related conditions. The compound's specific properties and therapeutic potential are subjects of ongoing research, with its chemical structure playing a crucial role in its interactions with biological systems.

1058-58-8

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1058-58-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1058-58-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,5 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1058-58:
(6*1)+(5*0)+(4*5)+(3*8)+(2*5)+(1*8)=68
68 % 10 = 8
So 1058-58-8 is a valid CAS Registry Number.

1058-58-8Relevant academic research and scientific papers

Synthesis of novel 16-spiro steroids: Spiro-7′-(aryl)tetrahydro-1H- pyrrolo[1,2-c][1,3]thiazolo-trans-androsterone hybrid heterocycles

Kanchithalaivan, Selvaraj,Kumar, Raju Ranjith,Perumal, Subbu

, p. 409 - 417 (2013/04/23)

The 1,3-dipolar cycloaddition of azomethine ylide derived in situ from the reaction of acenaphthylene-1,2-dione and 1,3-thiazolane-4-carboxylic acid to various exocyclic dipolarophiles synthesized from trans-androsterone and trans-dehydroandrosterone afforded a library of novel spiro[5′.2″] acenaphthylene-1″-one-spiro[16.6′]-(7′-aryl) -tetrahydro-1H-pyrrolo [1,2-c][1,3]thiazolo-trans-androsterone/ dehydroandrosterone hybrid heterocycles respectively. These reactions proceeded stereo-specifically affording a single isomer of the 16-spiro steroids in excellent yields.

Synthesis, characterization and biological evaluation of some 16E-arylidene androstane derivatives as potential anticancer agents

Guo, Hao,Wu, Haotian,Yang, Jin,Xiao, Yuling,Altenbach, Hans-Josef,Qiu, Guofu,Hu, Hao,Wu, Zhongyuan,He, Xianran,Zhou, Dingshan,Hu, Xianming

experimental part, p. 709 - 723 (2011/07/07)

A series of new 16E-arylidene androstane derivatives were synthesized and characterized. The new compounds were screened for their anticancer activities against the human cancer cell lines SW480, A549, HepG2 and HeLa in vitro using the MTT assay. The resu

Peracid Oxidation of 16-Arylidene- and 16-Alkylidene-17-oxo-steroids

Chagonda, Lameck S.,Marples, Brian A.

, p. 875 - 880 (2007/10/02)

Peracid oxidation of 16-arylidene- and 16-alkylidene-5α-androstan-17-ones (1) - (6) gave no α,β-unsaturated δ-lactones, but resulted mainly in products of direct oxidation of the olefinic double bond.

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