105852-63-9

Upstream product

• 556-24-1 methyl 3-methylbutanoate 
• 105852-42-4 2-<<3-(benzyloxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-(4S)-1,3-oxazolidin-5-yl>methyl>-3-methyl-(2S)-butyric acid 
• 114469-37-3 ((1S,2R)-1-Cyclohexylmethyl-2-hydroxy-3-iodo-propyl)-carbamic acid benzyl ester 
• 114469-35-1 3-<(benzyloxycarbonyl)amino>-4-cyclohexyl-1-iodo-2-<(trimethylsilyl)oxy>-(2R,3S)-butane 
• 105852-65-1 (2S)-2-[(4S,5S)-3-benzyloxycarbonyl-4-cyclohexylmethyl-2,2-dimethyl-1,3-oxazolidin-5-yl]methyl-N-butyl-3-methylbutanamide 
• 105852-50-4 3-(benzyloxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-5-(iodomethyl)-(4S,5R)-1,3-oxazolidine 

Downstream Products

• 114530-03-9 (2S,4S,5S)-5-[(S)-2-[(R)-2-Benzyl-3-(2-methyl-propane-2-sulfonyl)-propionylamino]-3-(1H-imidazol-4-yl)-propionylamino]-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid butylamide 
• 105851-89-6 2,2-Dimethyl-propionic acid (S)-1-[(S)-1-((1S,2S,4S)-4-butylcarbamoyl-1-cyclohexylmethyl-2-hydroxy-5-methyl-hexylcarbamoyl)-2-(1H-imidazol-4-yl)-ethylcarbamoyl]-2-phenyl-ethyl ester 
• 114469-22-6 (2S,4S,5S)-5-[(S)-2-[(S)-2-Benzyl-3-(2-methyl-propane-2-sulfonyl)-propionylamino]-3-(1H-imidazol-4-yl)-propionylamino]-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid butylamide 
• 105852-62-8 (2S,4S,5S)-5-[(S)-2-Amino-3-(1H-imidazol-4-yl)-propionylamino]-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid butylamide 

Relevant academic research and scientific papers

Synthesis and biological activity of some transition-state inhibitors of human renin

A series of renin inhibitors containing the dipeptide transition state mimics (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-7-methyloctanoic acid (Leu-(OH)-Val) and (2S,4S,5S)-5-amino-4-hydroxy-2-isopropyl-6-cyclohexylhexanoic acid (Cha-(OH)-Val) was prepared.