556-24-1 Usage
Description
Methyl isovalerate has a strong, pungent, apple-like odor and a
bitter flavor. It may be prepared by esterification of isovaleric acid
with methyl alcohol at the boil in the presence of concentrated H2SON4.
Chemical Properties
Different sources of media describe the Chemical Properties of 556-24-1 differently. You can refer to the following data:
1. Methyl isovalerate has a strong, pungent, apple-like odor and a bitter flavor. This compound is also reported to have an
herbaceous, fruity odor.
2. clear slightly yellow liquid
Occurrence
Reported found in the juice of a few varieties of Florida oranges, pineapple, apple, banana, bilberry, blueberry,
strawberry, melon, peas, peppermint oil, pepper, blue, Gruyere and parmesan cheese, coffee, honey, olive, mushroom, jackfruit,
cherimoya, sage, custard apple, nectarine, lamb’s lettuce and cape gooseberry
Preparation
By esterification of isovaleric acid with methyl alcohol at the boil in the presence of concentrated H2SO4.
Aroma threshold values
Detection: 4.4 to 44 ppb
Taste threshold values
Taste characteristics at 80 ppm: fruity, pineapple, apple with a juicy, fruit-like nuance
Synthesis Reference(s)
Tetrahedron Letters, 8, p. 4805, 1967 DOI: 10.1016/S0040-4039(01)89607-6
General Description
A colorless liquid. Flash point below 70°F. Less dense than water and insoluble in water. Vapors heavier than air. May be slightly toxic by ingestion and inhalation. Used to make other chemicals.
Air & Water Reactions
Highly flammable. Insoluble in water.
Reactivity Profile
Methyl isovalerate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Health Hazard
May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Check Digit Verification of cas no
The CAS Registry Mumber 556-24-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,5 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 556-24:
(5*5)+(4*5)+(3*6)+(2*2)+(1*4)=71
71 % 10 = 1
So 556-24-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O2/c1-4(2)5(3)6(7)8/h4-5H,1-3H3,(H,7,8)/p-1
556-24-1Relevant articles and documents
Bock,K.,Jensen,S.R.
, p. 753 (1978)
Electrochemical esterification via oxidative coupling of aldehydes and alcohols
Smeyne, Dylan,Verboom, Katherine,Bryan, Maria,LoBue, James,Shaikh, Abid
supporting information, (2021/03/26)
An electrolytic method for the direct oxidative coupling of aldehydes with alcohols to produce esters is described. Our method involves anodic oxidation in presence of TBAF as supporting electrolyte in an undivided electrochemical cell equipped with graphite electrodes. This method successfully couples a wide range of alcohols to benzaldehydes with yields ranging from 70 to 90%. The protocol is easy to perform at a constant voltage conditions and offers a sustainable alternative over conventional methods.
Selective hydrogenation of α,β-unsaturated carbonyl compounds on silica-supported copper nanoparticles
Mendes-Burak, Jorge,Ghaffari, Behnaz,Copéret, Christophe
supporting information, p. 179 - 181 (2019/01/04)
Silica-supported copper nanoparticles prepared via surface organometallic chemistry are highly efficient for the selective hydrogenation of various α,β-unsaturated carbonyl compounds yielding the corresponding saturated esters, ketones, and aldehydes in the absence of additives. High conversions and selectivities (>99%) are obtained for most substrates upon hydrogenation at 100-150 °C and under 25 bar of H2.
