1058672-07-3Relevant academic research and scientific papers
Enantioselective organocatalytic Michael additions to acrylic acid derivatives: Generation of all-carbon quaternary stereocentres
Rigby, Caroline L.,Dixon, Darren J.
, p. 3798 - 3800 (2008)
Acrylic esters, thioesters and N-acryloyl pyrrole have been identified as effective electrophiles in the enantioselective Michael addition reaction with β-keto ester pro-nucleophiles catalysed by a cinchona alkaloid derived bifunctional organocatalyst; enantiomeric excesses of up to 98% and yields of up to 96% can be obtained for a range of Michael acceptors and pro-nucleophiles. The Royal Society of Chemistry.
