Chemical Communications p. 3798 - 3800 (2008)
Update date:2022-07-30
Topics:
Rigby, Caroline L.
Dixon, Darren J.
Acrylic esters, thioesters and N-acryloyl pyrrole have been identified as effective electrophiles in the enantioselective Michael addition reaction with β-keto ester pro-nucleophiles catalysed by a cinchona alkaloid derived bifunctional organocatalyst; enantiomeric excesses of up to 98% and yields of up to 96% can be obtained for a range of Michael acceptors and pro-nucleophiles. The Royal Society of Chemistry.
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