105871-99-6Relevant articles and documents
Piperazinealkanol ester derivatives of indomethacin as dual inhibitors of 5-lipoxygenase and cyclooxygenase
Yamawaki,Suzuki,Ogawa
, p. 963 - 971 (1994)
Piperazinealkanol ester derivatives of indomethacin were prepared and tested for inhibitory activities against 5-lipoxygenase (5-LO) and cyclooxygenase (CO). They inhibited 5-hydroxyeicosatetraenoic acid (5-HETE) formation by the cytosol of guinea pig pol
Derivative of piperazine having anti-allergic and anti-inflammatory action
-
, (2008/06/13)
A piperazine derivative represented by the formula (I) below STR1 wherein R1 is lower alkyl or phenyl, R2 is hydrogen or lower alkyl, n is an integer of 2 to 10, is useful as an effective component of anti-inflammatory agent or antia