105872-02-4

Upstream product

• 105871-99-6 1-(3-tert-butyldimethylsilyloxypropyl)-4-phenacylpiperazine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 105871-98-5 1-(3-hydroxypropyl)-4-phenacylpiperazine 

Downstream Products

• 105871-80-5 [1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-acetic acid 2-{4-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-piperazin-1-yl}-1-phenyl-ethyl ester 

Relevant academic research and scientific papers

Piperazinealkanol ester derivatives of indomethacin as dual inhibitors of 5-lipoxygenase and cyclooxygenase

Piperazinealkanol ester derivatives of indomethacin were prepared and tested for inhibitory activities against 5-lipoxygenase (5-LO) and cyclooxygenase (CO). They inhibited 5-hydroxyeicosatetraenoic acid (5-HETE) formation by the cytosol of guinea pig pol

Derivative of piperazine having anti-allergic and anti-inflammatory action

A piperazine derivative represented by the formula (I) below STR1 wherein R1 is lower alkyl or phenyl, R2 is hydrogen or lower alkyl, n is an integer of 2 to 10, is useful as an effective component of anti-inflammatory agent or antia