105873-71-0

Upstream product

• 106-88-7 ethyloxirane 
• 103-71-9 phenyl isocyanate 
• 28832-55-5 2-Chlorobutanal 
• 124-38-9 carbon dioxide 
• 123265-53-2 2-Ethyl-1-phenyl-aziridine 

Relevant academic research and scientific papers

VanadiumV(salen) catalysed synthesis of oxazolidinones from epoxides and isocyanates

The combination of a vanadiumV(salen) complex V +O(salen) EtOSO3- and tetrabutylammonium bromide forms a highly active catalyst system for the reaction between epoxides and isocyanates leading to oxazolidinones.

Selective Formation of α-Cleavage Cycloadduct of Oxirane with Heterocumulene Promoted by High-Coordinated Trialkyltin Complexes

In the reaction of monosubstituted oxiranes and heterocumulenes, trialkyltin iodides coordinated by phosphine oxides effectively catalyzed the formation of heterocyles via cleavage at the substituted site in the oxirane ring, while other types of organotin complexes or noncomplexed organotin iodides promoted selective cleavage at the opposite site.A mechanistic investigation demonstrated that the coordination of phophine oxide promotes the reverse reaction of the oxirane-ring cleavage leading to the predominant formation of α-cleavage cycloadducts.

Regioselective Cycloaddition of 1,2-Disubstituted Aziridines to Heterocumulenes Catalyzed by Organoantimony Halides

In the presence of catalytic amounts of organoantimony(V) halides such as Ph4SbI, Ph4SbBr, Ph3SbBr2, and Ph3SbCl2, the cycloaddition of aziridines 1a-g with heterocumulenes (phenyl isothiocyanate, carbon disulfide, and carbon dioxide) selectively gave ring-expanded cycloadducts 3a-d, f, g and 6e by α-cleavage of the aziridine rings. - Key Words: Organoantimony halides / Aziridines, cycloaddition of, α-cleavage of / Heterocumulenes

Reduction of Aldehyde with Tributyltin Hydride-HMPA Combined System

Bu3-SnH-HMPA combined system is an efficient reagent for the reduction of aldehydes.The reaction proceeds in good yields, and chemoselective carbonyl reduction is achieved for the substrate which includes another reducible group.Moreover, the intermediate, tin alkoxide, undergoes further reaction such as the preparation of ethers and heterocyclic compounds in the one pot procedure.

Selective α-Cleavage Cycloaddition of Oxiranes with Heterocumulenes Catalyzed by Tetraphenylstibonium Iodide

A catalytic amount of tetraphenylstibonium iodide (1) promoted unusual cycloadditions of oxiranes with isocyanates or carbodiimides, forming 3,4-disubstituted oxazolidin-2-ones 2 and oxazolidin-2-imines 4 under very mild conditions, respectively.In partic

UNUSUAL CYCLOADDITION OF OXIRANES WITH ISOCYANATES CATALYZED BY TETRAPHENYLSTIBONIUM IODIDE; SELECTIVE FORMATION OF 3,4-DISUBSTITUTED OXAZOLIDINONES.

Tetraphenylstibonium iodide is a general and versatile catalyst for the selective formation of unusual cycloadducts, 3,4-disubstituted oxazolidinones, in the reaction of oxiranes with isocyanates.