N-{4-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-ylsulfamoyl]-phenyl}-succinamic acid is a complex organic compound with a molecular formula of C18H13FN4O4S3. It features a succinamic acid backbone, which is a derivative of succinic acid, with an amide group attached to the nitrogen atom. The compound also contains a phenyl ring, a fluorine atom, and a [1,3,4]thiadiazole ring, which is a five-membered heterocyclic ring with one sulfur and two nitrogen atoms. The thiadiazole ring is connected to a sulfamoyl group, which is a sulfonamide functional group. This chemical is known for its potential pharmaceutical applications, particularly as an angiotensin II receptor antagonist, which can be used in the treatment of hypertension and heart failure by blocking the action of angiotensin II, a potent vasoconstrictor.
1059-01-4
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Basic information
- Product Name: N-{4-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-ylsulfamoyl]-phenyl}-succinamic acid
- Synonyms:
- CAS NO:1059-01-4
- Molecular Formula:
- Molecular Weight: 450.471
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: N-{4-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-ylsulfamoyl]-phenyl}-succinamic acid(CAS DataBase Reference)
- NIST Chemistry Reference: N-{4-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-ylsulfamoyl]-phenyl}-succinamic acid(1059-01-4)
- EPA Substance Registry System: N-{4-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-ylsulfamoyl]-phenyl}-succinamic acid(1059-01-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1059-01-4(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 1059-01-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,5 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1059-01:
(6*1)+(5*0)+(4*5)+(3*9)+(2*0)+(1*1)=54
54 % 10 = 4
So 1059-01-4 is a valid CAS Registry Number.
1059-01-4Upstream product
- 831-38-9 2-(4-fluorobenzoyl)hydrazinecarbothioamide
- 980-45-0 4-acetylamino-N-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-yl]-benzenesulfonamide
- 942-70-1 5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine
- 108-30-5 succinic acid anhydride
- 852-39-1 4-amino-N-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-yl]-benzenesulfonamide
1059-01-4Downstream Products
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N-{4-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-ylsulfamoyl]-phenyl}-succinamic acid
