105902-32-7Relevant articles and documents
Copper-catalyzed meta-selective arylation of phenol derivatives: An easy access to m-aryl phenols
Maraswami, Manikantha,Hirao, Hajime,Loh, Teck-Peng
, p. 2302 - 2309 (2021/02/20)
Achieving selective meta-functionalization of phenols is a significant challenge. Accessing such compounds generally needs elevated temperature or incorporation of complex templates. Here, we report a general approach to achieve meta-arylated phenols with a simple and common directing group. This coppercatalyzed protocol proceeds with complete meta-selectivity and tolerates a variety of functional groups in both coupling partners. Computational studies have revealed that the reaction proceeded via a Heck-like pathway.
Synthesis of substituted phenols by using the ring-closing metathesis/isoaromatization approach
Yoshida, Kazuhiro,Narui, Rintaro,Imamoto, Tsuneo
experimental part, p. 9706 - 9713 (2009/10/02)
Ring-closing olefin metathesis (RCM) of 4-methylene-1,7-octadien-3-ones 2, followed by isomerization of the carbon-carbon double bond of 6-methylene-2-cyclohexenones 3 from exo to endo, produced various phenols 4. As an application of the method, the RCM/
