105907-65-1

Basic information

• Product Name: 1-(3,5-Dimethylphenyl)piperazine
• Synonyms: Piperazine, 1-(3,5-dimethylphenyl)- (9CI)
• CAS NO: 105907-65-1
• Molecular Formula: C₁₂H₁₈N₂
• Molecular Weight: 190.28472
• Product Categories: PIPERIDINE
• Mol File: 105907-65-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 339 °C at 760 mmHg
• Flash Point: 156.6 °C
• Appearance: Gray power
• Density: 0.999 g/cm³
• Vapor Pressure: 9.49E-05mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 1-(3,5-Dimethylphenyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-Dimethylphenyl)piperazine(105907-65-1)
• EPA Substance Registry System: 1-(3,5-Dimethylphenyl)piperazine(105907-65-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 105907-65-1(Hazardous Substances Data)

Usage

General Description

1-(3,5-Dimethylphenyl)piperazine is a chemical compound belonging to the class of organic compounds known as diarylethers. Diarylethers are a group of organic compounds containing two aryl groups connected by an ether group. This chemical compound appears in a solid powder form featuring a benzene ring with adjacent methyl groups and a piperazine substitute, giving it properties that make it useful in a variety of chemical reactions. However, the specifics of its uses in industrial, medical, or commercial settings haven't been explicitly detailed in related literature, implying the need for further research.

InChI:InChI=1/C12H18N2/c1-10-7-11(2)9-12(8-10)14-5-3-13-4-6-14/h7-9,13H,3-6H2,1-2H3

Upstream product

• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 
• 108-69-0 3,5-dimethylaminoaniline 
• 110-85-0 piperazine 
• 773-01-3 2,4,6-trimethylpyrylium tetrafluoroborate 

Downstream Products

• 120004-75-3 7-{3-[4-(3,5-Dimethyl-phenyl)-piperazin-1-yl]-propoxy}-3,4-dihydro-1H-quinolin-2-one 
• 1553930-25-8 N-{2-[4-(3,5-dimethylphenyl)piperazin-1-yl]ethyl}-2-quinoxalinecarboxamide 
• 1553930-18-9 N-{2-[4-(3,5-dimethylphenyl)piperazin-1-yl]ethyl}-2-naphthalenecarboxamide 
• 1267674-87-2 C₁₄H₂₃N₃ 
• 1553930-04-3 N-{2-[4-(3,5-dimethylphenyl)piperazin-1-yl] ethyl }phthalimide 
• 1430810-69-7 1-(biphenyl-2-ylmethyl)-4-(3,5-dimethylphenyl)piperazine 
• 1359979-08-0 1-[(3,5-dimethoxyquinoxalin-2-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine 
• 1359979-06-8 1-(3,5-dimethylphenyl)-4-[(3-methoxy-5-methylquinoxalin-2-yl)aminocarbonyl]piperazine 
• 1258003-34-7 1-[(2,5-dimethoxyquinoxalin-3-yl)aminocarbonyl]-4-(3,5-dimethylphenyl)piperazine 

Relevant articles and documents

Practical method for parallel synthesis of diversely substituted 1-phenylpiperazines

A simple and practical method to prepare 'libraries' of substituted 1-phenylpiperazine building blocks in parallel format has been developed.

SYNTHESE DE N,N-DIALKYL-3,5-DIALKYL-ANILINES A PARTIR DES SELS DE TRIALKYL-2,4,6-PYRYLIUM

We have optimized through an experimental design the synthesis of N,N-diethyl-3,5-dimethylaniline from 2,4,6-trimethylpyrylium terafluoroborate (I) and diethylamine in a new reaction medium (acetonitrile/triethylamine).Optimal conditions have been applied with high yields to the synthesis of various 3,5-dimethylanilines derived from I and dimethylamine, morpholine, N-methylpiperazine, piperazine, dihexylamine, piperidine, and pyrrolidine respectively. 2-Alkyl-4,6-dimethylpyrylium tetrafluoroborates react regioselectively with diethylamine to afford N,N-diethyl-3-alkyl-5-methyl anilines under these conditions.