105930-84-5

Upstream product

• 118068-35-2 3',5'-bis-O-(tert-butyldiphenylsilyl)-thymidine 
• 175020-66-3 2-deoxy-3,5-di-O-(tert-butyldiphenylsilyl)-D-ribonolactone 
• 148903-86-0 tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxytetrahydrofuran-2-yl)methoxy)diphenylsilane 
• 34371-14-7 2-deoxy-D-ribonolactone 
• 50-89-5 thymidine 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 105930-86-7 (4aS,6R,7S,7aS)-3-Benzyloxy-7-(tert-butyl-diphenyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-4a,6,7,7a-tetrahydro-furo[3,2-e][1,3,4]oxadiazine-1-carboxylic acid benzyl ester 
• 130277-32-6 ((2R,3S)-3-(tert-butyldiphenylsilyloxy)-2,3-dihydrofuran-2-yl)methanol 
• 105930-90-3 C₅₄H₆₂N₂O₈Si₂ 
• 105930-94-7 C₂₂H₂₆N₂O₈ 
• 173256-58-1 3-[(2R,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2,5-dihydro-furan-2-yl]-5-chloro-pyrazine-2,6-diamine 

Relevant academic research and scientific papers

Organocatalytic Conversion of Nucleosides to Furanoid Glycals

A class of organocatalysts that are highly active for the conversion of 2′-deoxynucleosides to furanoid glycals have been discovered. These phosphorimides, (Ph2PS)2NH and (Ph2PSe)2NH, were shown to effectively mediate persilylation of 2′-deoxynucleosides

Synthesis of erythro and threo furanoid glycals from 1- and 2-phenylselenenyl-carbohydrate derivatives

Differently protected erythro and threo furanoid glycals were synthesized by selenoxide elimination when phenyl 1-selenoglycosides were treated in oxidizing conditions (tBuOOH, Ti(OiPr)4, Et2iPrN). Th

Facile preparation of protected furanoid glycals from thymidine

The synthesis of O-silyl- and O-acyl-protected furanose glycals from free thymidine was investigated. The method of glycal formation reported by Pedersen et al. was successfully expanded to include 5-ester (toluoyl) protected glycals as well as various combinations of 5'-ester and 3- and 5- tert-butyldimethylsilyl and tert-butyldiphenylsilyl protection. Gram quantities of furanoid glycals can be prepared in a few days in two-four steps in overall yields ranging from 17 to 80%.