105938-45-2Relevant academic research and scientific papers
2-Aryl-N-acyl indole derivatives as liver X receptor (LXR) agonists
Kher, Sunil,Lake, Kirk,Sircar, Ila,Pannala, Madhavi,Bakir, Farid,Zapf, James,Xu, Kui,Zhang, Shao-Hui,Liu, Juping,Morera, Lisa,Sakurai, Naoki,Jack, Rick,Cheng, Jie-Fei
, p. 4442 - 4446 (2008/02/11)
Structure-activity relationship studies on a series of Boc-indole derivatives as LXR agonists are described. Compound 1 was identified as an LXR agonist through structure-based virtual screening followed by high-throughput gene profiling. Replacement of t
