105949-86-8 Usage
Type
Trioxolane
Trioxolanes are six-membered cyclic peroxides, characterized by the presence of three oxygen atoms in the ring.
Antimalarial properties
Known for their potential use in medicine
Trioxolanes, including 1,2,4-Trioxolane-3-carboxylic acid, 3-methyl-, methyl ester (9CI), have been studied for their ability to combat malaria, a disease caused by parasites transmitted through mosquito bites.
Methyl ester form
Stable compound
The methyl ester form of the compound is considered stable, making it suitable for various chemical reactions and research purposes.
Reactivity
Potential reactivity
Due to its peroxide nature, 1,2,4-Trioxolane-3-carboxylic acid, 3-methyl-, methyl ester (9CI) may exhibit reactivity under certain conditions, which should be taken into account when handling the compound.
Toxicity
Potential toxicity
Safety protocols
Handle with care
When working with 1,2,4-Trioxolane-3-carboxylic acid, 3-methyl-, methyl ester (9CI), it is crucial to follow appropriate safety measures, such as wearing personal protective equipment (PPE) and working in a well-ventilated area.
Research purposes
Potential applications in chemical reactions and studies
The stable nature of the methyl ester form of the compound makes it a candidate for various research applications, including the development of new drugs or the study of its chemical properties.
Synonyms
1,2,4-Trioxolane-3-carboxylic acid, 3-methyl-, methyl ester (9CI)
The compound may be referred to by different names in various databases or literature, but the 9CI name provides a unique identifier for the compound.
Check Digit Verification of cas no
The CAS Registry Mumber 105949-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,9,4 and 9 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 105949-86:
(8*1)+(7*0)+(6*5)+(5*9)+(4*4)+(3*9)+(2*8)+(1*6)=148
148 % 10 = 8
So 105949-86-8 is a valid CAS Registry Number.
105949-86-8Relevant articles and documents
About the Ozone Cleavage of Chloroprene and of 2-Chloro-3-methyl-1,3-butadiene in Methanol
Griesbaum, Karl,Meister, Martin
, p. 1573 - 1580 (2007/10/02)
Monoozonolyses of chloroprene (1a) and of 2-chloro-3-methyl-1,3-butadiene (1b) in methanol occur with more than 90percent at the non-chlorinated double bonds to afford the corresponding α,β-unsaturated oxo compounds 2 with selectivities of 96 and 80percent respectively.The latter subsequently react with methanol, and 2a also with the complementary fragment methoxymethyl hydroperoxide (5).The α,β-unsaturated methoxy hydroperoxides 3 which have also been obtained, are less stable than similarly structured, non-α-chlorinated methoxy hydroperoxides.Diozonolyses of 1a and 1b in methanol afforded in 50-60percent the corresponding α-oxocarboxylates (21) and/or the corresponding ketals.In addition, anomalous products were obtained viz. ca. 15percent of methyl hydroxyacetate (12d) from 1a and 1b, as well as ca. 30percent of dimethyl oxalate (27b) from 1a and ca. 35percent of methyl acetate (13) from 1b.The modes of formation of these products have been postulated according to model reactions.
