105971-45-7Relevant articles and documents
Dichotomy of reductive addition of amines to cyclopropyl ketones vs pyrrolidine synthesis
Afanasyev, Oleg I.,Tsygankov, Alexey A.,Usanov, Dmitry L.,Chusov, Denis
, p. 5968 - 5970 (2016)
An interesting catalytic dichotomy was discovered: switching between simple ligand-free catalysts leads to fundamentally different outcomes of reductive reaction between amines and α-carbonylcyclopropanes. Whereas a rhodium catalyst leads to the tradition
Investigation towards the reductive amination of levulinic acid by B(C6F5)3/hydrosilane system
He, Jianghua,Wang, Tianlong,Xu, Hai,Zhang, Yuetao
, (2020/08/11)
The selective transformation of the renewable biomass resources into the highly value-added platform chemicals is essentially important for sustainable chemistry. Here we report a simple and highly efficient strategy for the synthesis of N-heterocyclic co
Metal-Free Synthesis of N-Aryl-Substituted Azacycles from Cyclic Ethers Using POCl3
La, Minh Thanh,Kang, Soosung,Kim, Hee-Kwon
, p. 6689 - 6696 (2019/06/14)
A facile method for the synthesis of N-aryl-substituted azacycles from arylamines and cyclic ethers has been developed. In this study, arylamines were treated with cyclic ethers in the presence of POCl3 and DBU to provide five- A nd six-membered azacycles. Using this method, various azacycloalkanes, isoindolines, and tetrahydroisoquinolines were prepared in high yields. This synthetic method offers an efficient approach to the production of azacycles from cyclic ethers.
