105986-54-7

Basic information

• Product Name: ethyl 4-(4-broMophenyl)butanoate
• Synonyms: ethyl 4-(4-broMophenyl)butanoate;Benzenebutanoic acid, 4-broMo-, ethyl ester;4-(4-Bromo-phenyl)-butyric acid ethyl ester
• CAS NO: 105986-54-7
• Molecular Formula: C₁₂H₁₅BrO₂
• Molecular Weight: 271.1503
• Mol File: 105986-54-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 330.711°C at 760 mmHg
• Flash Point: 153.809°C
• Appearance: /
• Density: 1.304g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.526
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: ethyl 4-(4-broMophenyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-broMophenyl)butanoate(105986-54-7)
• EPA Substance Registry System: ethyl 4-(4-broMophenyl)butanoate(105986-54-7)

Safety Data

• Hazardous Substances Data: 105986-54-7(Hazardous Substances Data)

Usage

General Description

Ethyl 4-(4-bromophenyl)butanoate is a chemical compound that belongs to the ester family. It is formed by the condensation of 4-bromobenzophenone and ethyl butyrate. It is a colorless liquid with a sweet, fruity odor, and is commonly used in the food and fragrance industries. It is also used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Ethyl 4-(4-bromophenyl)butanoate is also known for its potential use as a flavoring and fragrance ingredient, and for its insecticidal and antimicrobial properties. However, it is important to handle this compound with care, as it may cause skin and eye irritation upon contact.

InChI:InChI=1/C12H15BrO2/c1-2-15-12(14)5-3-4-10-6-8-11(13)9-7-10/h6-9H,2-5H2,1H3

Upstream product

• 64-17-5 ethanol 
• 35656-89-4 4-(4-bromophenyl)butanoic acid 
• 108-86-1 bromobenzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 623-51-8 ethyl 2-sulfanylacetate 
• 19493-09-5 Methylenetriphenylphosphorane 
• 623-73-4 diazoacetic acid ethyl ester 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 27200-79-9 p-bromophenylacetaldehyde 
• 6340-79-0 4-oxo-4-(4-bromophenyl)butanoic acid 
• 589-87-7 1,4-bromoiodobenzene 
• 104089-17-0 ethyl 4-(iodozincio)butanoate 
• 14062-25-0 Ethyl 4-bromophenylacetate 

Downstream Products

• 98453-60-2 6-bromo-3,4-dihydro-4,4-dimethylnaphthalen-1(2H)-one 
• 117713-14-1 4-(but-3-en-1-yl)-4'-methyl-1,1'-biphenyl 
• 30913-87-2 4-(4-bromophenyl)-4-oxobutanoic acid ethyl ester 
• 128994-29-6 (S)-(-)-γ-(p-Bromophenyl)-γ-butyrolactone 
• 126135-43-1 (R)-(+)-γ-(p-Bromophenyl)-γ-butyrolactone 
• 74003-07-9 ethyl 4-<4-(1-imidazolyl)phenyl>butyrate 

Relevant articles and documents

Visible-light induced metal-free cascade Wittig/hydroalkylation reactions

Cascade reactions are green and powerful transformations for building multiple carbon-carbon bonds in one step. Through a relay olefination and radical addition process, we were able to develop the cascade Wittig/hydroalkylation reactions induced by visible light. This metal-free radical approach features mild conditions, robustness, and excellent functionality compatibility. It allows access to saturated C3 homologation products directly from aldehydes or ketones. The synthetic utility of this method is demonstrated by a two-step synthesis ofindolizidine 209D.

Combined Photoredox/Enzymatic C?H Benzylic Hydroxylations

Chemical transformations that install heteroatoms into C?H bonds are of significant interest because they streamline the construction of value-added small molecules. Direct C?H oxyfunctionalization, or the one step conversion of a C?H bond to a C?O bond, could be a highly enabling transformation due to the prevalence of the resulting enantioenriched alcohols in pharmaceuticals and natural products,. Here we report a single-flask photoredox/enzymatic process for direct C?H hydroxylation that proceeds with broad reactivity, chemoselectivity and enantioselectivity. This unified strategy advances general photoredox and enzymatic catalysis synergy and enables chemoenzymatic processes for powerful and selective oxidative transformations.

Detailed mechanistic studies on palladium-catalyzed selective C-H olefination with aliphatic alkenes: A significant influence of proton shuttling

Directing group-assisted regioselective C-H olefination with electronically biased olefins is well studied. However, the incorporation of unactivated olefins has remained largely unsuccessful. A proper mechanistic understanding of olefination involving un