105995-73-1

Basic information

• Product Name: 5-BROMO-2-ETHYNYL-THIOPHENE
• Synonyms: 5-BROMO-2-ETHYNYL-THIOPHENE;2-BroMo-5-ethynylthiophene
• CAS NO: 105995-73-1
• Molecular Formula: C₆H₃BrS
• Molecular Weight: 187.05702
• Mol File: 105995-73-1.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-BROMO-2-ETHYNYL-THIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-ETHYNYL-THIOPHENE(105995-73-1)
• EPA Substance Registry System: 5-BROMO-2-ETHYNYL-THIOPHENE(105995-73-1)

Safety Data

• Hazardous Substances Data: 105995-73-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
5-BROMO-2-ETHYNYL-THIOPHENE is used as a building block in various organic synthesis reactions for the formation of complex organic molecules. Its unique structure and reactivity contribute to the creation of a wide range of compounds.
Used in Pharmaceutical Industry:
5-BROMO-2-ETHYNYL-THIOPHENE is used as a key intermediate in the synthesis of pharmaceuticals. Its presence in the molecular structure can impart specific properties and functionalities, making it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
5-BROMO-2-ETHYNYL-THIOPHENE is used as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness and selectivity in controlling pests and weeds.
Used in Advanced Materials:
5-BROMO-2-ETHYNYL-THIOPHENE is used in the development of materials with advanced properties, such as high thermal stability, electrical conductivity, or specific optical characteristics. Its unique structure allows for the creation of materials with tailored properties for various applications.
Used in Organic Electronics:
5-BROMO-2-ETHYNYL-THIOPHENE is used in the field of organic electronics, where it can be incorporated into organic semiconductors for use in electronic devices such as organic light-emitting diodes (OLEDs) and organic photovoltaic cells. Its electronic properties make it a promising candidate for improving the performance and efficiency of these devices.

Upstream product

• 4701-17-1 5-bromo-2-thiophencarboxaldehyde 
• 90965-06-3 dimethyl 1-(1-diazo-2-oxopropyl)phosphonate 
• 606925-57-9 ((5-bromothiophene-2-yl)ethynyl)trimethylsilane 

Relevant articles and documents

Bis(het)aryl-1,2,3-triazole quinuclidines as α7 nicotinic acetylcholine receptor ligands: Synthesis, structure affinity relationships, agonism activity, [18F]-radiolabeling and PET study in rats

In this paper we describe the design and synthesis of bis(Het)Aryl-1,2,3-triazole quinuclidine α7R ligands using an efficient three-step sequence including a Suzuki-Miyaura cross coupling reaction with commercially available and home-made boron derivatives. The exploration of SAR required the preparation of uncommon boron derivatives. Forty final drugs were tested for their ability to bind the target and nine of them exhibited Ki values below nanomolar concentrations. The best scores were always obtained when the 5-phenyl-2-thiophenyl core was attached to the triazole. The selectivity of these compounds towards the nicotinic α4β2 and serotoninergic 5HT3 receptors was assessed and their brain penetration was quantified by the preparation and in vivo evaluation of two [18F] radiolabelled derivatives. It can be expected from our results that some of these compounds will be suitable for further developments and will have effects on cognitive disorders.

1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF

A compound having the following general formula (I): wherein: X is a nitrogen atom and Y is a carbon atom; orX is a carbon atom and Y is a nitrogen atom;the Ar group is an aryl or heteroaryl group; andthe RN and RN′ groups, together with the carbon atoms

Solution-processable polyphenylphenyl dendron bearing molecules for highly efficient blue light-emitting diodes

(Chemical Equation Presented) Novel solution-processable blue light-emitting materials Blue A-D, bearing a polyphenylphenyl dendron, have been synthesized and characterized. The energy levels and band gaps can be facilely tuned by changing the central aro