106018-98-8Relevant articles and documents
A method for synthesis of fluorine compounds using abnormal Grignard reaction of halothane. II. Reaction with aldehydes and unsaturated ketones
Takagi,Takesue,Isowaki,Koyama,Ando,Kumadaki
, p. 1071 - 1075 (1995)
In an abnormal Grignard reaction of halothane, the primary Grignard reagent reacts with another mole of halothane to give 1-bromo-1-chloro- 2,2,2-trifluoroethylmagnesium bromide, which in turn reacts with a carbonyl compound to give 1-bromo-1-chloro-2,2,2
Efficient Carbonyl Addition of Polyfluorochloroethyl, -ethylidene, and -ethenyl Units by Means of 1,1,1-Trichloro-2,2,2-trifluoroethane and Zinc
Fujita, Makoto,Hiyama, Tamejiro
, p. 4377 - 4384 (2007/10/02)
Thermally stable zinc carbenoid CF3CCl2ZnCl was prepared from 1,1,1-trichloro-2,2,2-trifluoroethane and zinc powder in N,N-dimethylformamide and was allowed to add to carbonyls of aldehydes and α-keto esters in excellent yields to give 1-substituted 2,2-d