106023-86-3Relevant academic research and scientific papers
Rhodium-catalyzed asymmetric hydrosilylation of ketones employing a new ligand embodying the bis(oxazolinyl)pyridine moiety
Ghoshal, Atanu,Sarkar, Asit R.,Manickam, Govindaswamy,Kumaran, R. Senthil,Jayashankaran
scheme or table, p. 1459 - 1462 (2010/08/19)
A general approach to new ligands embodying bis(oxazolinyl)pyridine has been developed, employing palladium-catalyzed Suzuki coupling and base-mediated cyclization as pivotal steps. A rhodium catalyst derived from the ligand 4-(4-ethylphenyl)-2,6-bis(4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine gave excellent enantioselectivity in the asymmetric hydrosilylation of ketones. In addition the electronic effect of remote substituents on the catalytic activity of rhodium catalyst was studied.
