10604-52-1Relevant academic research and scientific papers
Trifluoromethyl group in the synthesis of heterocyclic compounds: New and efficient synthesis of 3-aryl-4-aminocinnolines
Kiselyov, Alexander S.
, p. 1383 - 1386 (1995)
A novel base-induced transformation of hydrozones 3a-f derived from trifluoromethylaryl ketones and arylhydrazines was found to produce 3-aryl-4-aminocinnolines 4a-g in 52-75% yield. The initial step of the reaction is believed to involve abstraction of H
