106053-83-2

Upstream product

• 3892-93-1 1-(3,4-dimethoxyphenyl)-2-phenylethane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 118199-01-2 2,2-dibromo-1-(3,4-dimethoxyphenyl)ethene 
• 4302-52-7 4-ethynylveratrole 
• 1185881-58-6 5-(2-(3,4-dimethoxyphenethyl)benzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1185881-90-6 2-(3,4-dimethoxyphenethyl)benzaldehyde 
• 1185881-84-8 2-(3,4-dimethoxyphenylethynyl)benzaldehyde 

Relevant academic research and scientific papers

Functionalization of Csp3-H bond-Sc(OTf)3-catalyzed domino 1,5-hydride shift/cyclization/Friedel-Crafts acylation reaction of benzylidene Meldrum's acids

Under Sc(OTf)3 catalysis, benzylidene Meldrum's acids bearing a tethered p-methoxyphenethyl group were observed to undergo a [1,5]-hydride shift/cyclization at room temperature, representing a mild Csp3-H bond functionalization. The resulting spiro Meldrum's acid intermediates then underwent intramolecular Friedel-Crafts acylation, completing the one-pot, domino reaction. The reported protocol generates the 6-6-5-6 tetracyclic core of tetrahydrobenzo[b]fluoren-11-ones.

Syntheses og Stilbenes with a C2-Sidechain in o-Position and of their Deuteriated Analogues

Syntheses of o-(β-aminoethyl)-stilbene-urethanes (types 1, 2 and 3) and o-(β-phenethyl)-stilbenes 4 are described.The urethanes are obtained by degradation of 1-benzyl-1,2,3,4-tetrahydroisoquinolines with ethylchloroformate; 4 is synthesized by reduction of desoxybenzoines, followed by o-formylation and Wittig-reaction.The deuteriated isotopomers were obtained via the corresponding deuteriated precursors. - Keywords: Stilbenes, o-substituted; Deuteriated compounds