106064-57-7

Basic information

• Product Name: [(S)-1-(2-Benzyloxy-ethyl)-3-iodo-hex-5-enyloxy]-tert-butyl-diphenyl-silane
• CAS NO: 106064-57-7
• Molecular Weight: 598.639
• Mol File: 106064-57-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(S)-1-(2-Benzyloxy-ethyl)-3-iodo-hex-5-enyloxy]-tert-butyl-diphenyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-1-(2-Benzyloxy-ethyl)-3-iodo-hex-5-enyloxy]-tert-butyl-diphenyl-silane(106064-57-7)
• EPA Substance Registry System: [(S)-1-(2-Benzyloxy-ethyl)-3-iodo-hex-5-enyloxy]-tert-butyl-diphenyl-silane(106064-57-7)

Safety Data

• Hazardous Substances Data: 106064-57-7(Hazardous Substances Data)

Upstream product

• 106064-50-0 5-Benzyloxy-3-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid isobutyl ester 
• 106064-53-3 8-(benzyloxy)-6-((tert-butyldiphenylsilyl)oxy)-4-hydroxy-1-octene 
• 106064-52-2 (S)-5-(benzyloxy)-3-(tert-butyldiphenylsiloxy)pentanal 
• 106064-51-1 5(S)-(benzyloxy)-3-((tert-butyldiphenylsilyl)oxy)pentanol 
• 106064-33-9 isobutyl 5-(benzyloxy)-3-oxopentanoate 
• 106064-44-2 isobutyl 5-(benzyloxy)-3-hydroxypentanoate 
• 3587-60-8 Benzyloxymethyl chloride 
• 106064-55-5 Methanesulfonic acid (S)-1-allyl-5-benzyloxy-3-(tert-butyl-diphenyl-silanyloxy)-pentyl ester 

Downstream Products

• 88818-17-1 (R)-1-phenylmethoxyoct-7-en-3-ol 
• 106064-59-9 [(R)-1-(2-Benzyloxy-ethyl)-hex-5-enyloxy]-tert-butyl-diphenyl-silane 

Relevant articles and documents

Substrate modification as a means of enhancing the enantioselectivity of microbial reductions of β-keto esters. An (R)- or (S )-1,3,5-trihydroxypentane synthon

The enantioselectivity of yeast-mediated reduction of 5-(benzyloxy)-3-oxopentanoate esters can be optimized by simple selection of a suitable ester alkoxy group. The resulting chiral 5-(benzyloxy)-3-hydroxypentanoates with > 95% ee can serve as either an (R)- or (S)-1,3,5-trihydroxypentane synthon for asymmetric syntheses. The synthesis of a key optically active intermediate for (S)-(-)-lipoic acid is provided as an example.