1060668-63-4Relevant academic research and scientific papers
Bromo- or Methoxy-Group-Promoted Umpolung Electron Transfer Enabled, Visible-Light-Mediated Synthesis of 2-Substituted Indole-3-glyoxylates
Vidyasagar, Adiyala,Shi, Jinwei,Kreitmeier, Peter,Reiser, Oliver
supporting information, (2018/11/23)
A visible-light-mediated radical tandem cyclization of ortho-isocyano-α-bromo cinnamates to 2-substituted indole-3-glyoxylates is achieved by formation of both C-C/C-S and C-O bonds. The reaction proceeds through a hitherto unprecedented bromine- or metho
Facile access to 2-arylindolines and 2-arylindoles by microwave-assisted tandem radical cyclization
Prediger, Inga,Weiss, Torsten,Reiser, Oliver
experimental part, p. 2191 - 2198 (2009/04/06)
A new route providing access to 2-arylindoles has been developed. The synthesis consists of a tin-mediated tandem radical cyclization of appropriate precursors to form 2,3-disubstituted dihydroindoles, which in turn are oxidized to yield the corresponding 2-arylindoles. The reactions proceed smoothly under microwave irradiation, furnishing the desired products in good yields. Georg Thieme Verlag Stuttgart.
